MYD88

Gene Symbol	MYD88
Entrez Gene	444881
Alt Symbol	-
Species	Bovine
Gene Type	protein-coding
Description	myeloid differentiation primary response 88
Other Description	myeloid differentiation factor 88|myeloid differentiation primary response gene (88)|myeloid differentiation primary response gene 88|myeloid differentiation primary response protein MyD88
Swissprots	Q599T9 Q49BZ6 Q49CF6 Q6GV22
Accessions	DAA17130 Q599T9 AJ853453 CAH68521 AY634627 AAT48485 AY934808 AAY16578 AY937381 AAY22119 BC102851 AAI02852 XM_005222379 XP_005222436 XR_814359 NM_001014382 NP_001014404
Function	Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine. {ECO:0000269|PubMed:17936907, ECO:0000269|PubMed:18760477}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Top Pathways	Herpes simplex infection, Legionellosis, Tuberculosis, Pertussis, Salmonella infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics

Myeloid differentiation primary response protein MyD88 (MYD88), Bovine, ELISA Kit - CSB-EL015282BO from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Myeloid differentiation primary response protein MyD88 (MYD88), Bovine, ELISA Kit - E11M0411 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Myeloid differentiation primary response protein MyD88, MYD88, Bovine, ELISA Kit - E1707b from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t

Myeloid Differentiation Factor 88, ELISA Kit - MBS064419 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

myeloid differentiation primary response gene (88) , ELISA Kit - MBS916548 from MyBioSource Category ELISA Kit Prices $550.00, $795.00, $2,890.00, $5,465.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of bovine MYD88 is typically less than 6.25 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 25 pg/ml -1600 pg/ml.

Bovine Myeloid differentiation primary response protein MyD88(MYD88) ELISA kit - CSB-EL015282BO from Cusabio Category ELISA Kit Sensitivity 3.12pg/ml Range 25 pg/ml-1600 pg/ml

Bovine MYD88 ELISA Kit - E090528 from Biobool Category ELISA Kit

Myeloid differentiation primary response protein MyD88, ELISA Kit - MBS2883253 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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