SCN9A

Gene Symbol	SCN9A
Entrez Gene	6335
Alt Symbol	ETHA, FEB3B, GEFSP7, HSAN2D, NE-NA, NENA, Nav1.7, PN1, SFNP
Species	Human
Gene Type	protein-coding
Description	sodium channel, voltage gated, type IX alpha subunit
Other Description	hNE-Na|neuroendocrine sodium channel|peripheral sodium channel 1|sodium channel protein type 9 subunit alpha|sodium channel protein type IX subunit alpha|sodium channel, voltage-gated, type IX, alpha polypeptide|sodium channel, voltage-gated, type IX, alpha subunit|voltage-gated sodium channel alpha subunit Nav1.7|voltage-gated sodium channel subunit alpha Nav1.7
Swissprots	Q70HX2 A1BUH5 Q8WTU1 Q70HX1 Q15858 Q6B4S0 Q6B4R9 Q8WWN4 Q6B4S1
Accessions	AAY14794 AAZ77737 CAE45644 CAE45645 EAX11314 EAX11315 EAX11316 Q15858 AJ277393 AJ310882 CAC84550 AJ310883 CAC84551 AJ310897 CAC84537 AK307549 AL517958 AY682084 AAT85833 AY682085 AAT85834 AY682086 AAT85835 BU742924 DQ857292 ABI51981 X82835 CAA58042 XM_005246757 XP_005246814 XM_011511616 XP_011509918 XM_011511617 XP_011509919 XM_011511618 XP_011509920 XM_011511619 XP_011509921 NM_002977 NP_002968
Function	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Multi-pass membrane protein. Note=In neurite terminals. {ECO:0000250}.
Tissue Specificity	Expressed strongly in dorsal root ganglion, with only minor levels elsewhere in the body, smooth muscle cells, MTC cell line and C-cell carcinoma. Isoform 1 is expressed preferentially in the central and peripheral nervous system. Isoform 2 is expressed preferentially in the dorsal root ganglion. {ECO:0000269|PubMed:15178348, ECO:0000269|PubMed:15302875, ECO:0000269|PubMed:7720699, ECO:0000269|PubMed:9169448}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Nav1.7 peptide - ab102727 from Abcam Category Peptide

Human Nav1.7 protein fragment - ab114304 from Abcam Category Protein Source Wheat germ Species Human

Nav1.7 peptide - ab192016 from Abcam Category Peptide

SCN9A / Nav1.7 Antibody Blocking Peptide - LS-E27758 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SCN9A / Nav1.7 Antibody Blocking Peptide - LS-E29701 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Nav1.7 Partial Recombinant Protein - H00006335-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Goat anti SCN9A antibody Immunizing peptide - orb66277 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Nav1.7 Blocking Peptide - abx063246 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Nav1.7 Peptide - AC21-2569-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SCN9A / PN1 - H00006335-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SCN9A / PN1 - H00006335-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SCN9A Peptide - 42-870P from ProSci Category Peptide

Recombinant Human SCN9A - SCN9A-27560TH from Creative Biomart Category Protein Source Wheat germ

Nav1.7 Blocking Peptide - CBP2052 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

Na+ CP type α-pan (E1476) Peptide - BS3558P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Na+ CP type IXα Peptide - BS5813P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Na+ CP type IXα (R692) Peptide - BS9164P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Sodium channel protein type 9 subunit alpha... - pep0283 from Covalab Category Protein Species Human, Mouse, Rat

NaV1.7, Peptide - MBS427541 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

SCN9A Peptide, Human - M34GP13875H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human CellExp™ Serpin E2 / PN1, Human recombinant - 268-11112-1 from RayBiotech Category Protein Species Human

Sodium channel protein type 9 subunit alpha (SCN9A), Recombinant Protein - MBS7073654 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Nav1.7 Recombinant Protein Antigen - NBP2-57651PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Human PN1 protein - orb55916 from Biorbyt Category Protein Species Human

SCN9A peptide - orb217915 from Biorbyt Category Peptide Species Human, Mouse

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