Gene Symbol | TMED9 |
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Entrez Gene | 54732 |
Alt Symbol | GMP25, HSGP25L2G, p25 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane emp24 protein transport domain containing 9 |
Other Description | glycoprotein 25L2|gp25L2 protein|p24 family protein alpha-2|p24alpha2|transmembrane emp24 domain-containing protein 9 |
Swissprots | Q8WZ61 Q14437 Q9BVK6 |
Accessions | EAW84966 EAW84967 EAW84968 Q9BVK6 AF441399 AAL35268 AK298435 BAG60656 AK313292 BAG36099 BC001123 AAH01123 BG830564 X90872 CAA62380 NM_017510 NP_059980 |
Function | Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer- dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB. {ECO:0000269|PubMed:10852829, ECO:0000269|PubMed:14600267, ECO:0000269|PubMed:16595549, ECO:0000269|PubMed:18287528, ECO:0000269|PubMed:19296914}. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Cycles between compartments of the early secretatory pathway. |
Human TMED9 full length protein - ab162822 from Abcam
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TMED9 Antibody Blocking Peptide - LS-E2307 from LifeSpan Bioscience
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Recombinant Human TMED9 Protein - H00054732-P01 from Novus Biologicals
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TMED9-Antibody-C-term-Blocking-peptide - BP13250b from Abgent, a WuXi AppTec company
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Human TMED9 (His Tag) protein - orb232346 from Biorbyt
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Human GP25L2 protein - orb245215 from Biorbyt
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Human TMED9 (Fc Tag) protein - orb232345 from Biorbyt
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TMED9 - H00054732-P01-10 from Acris Antibodies
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TMED9 - H00054732-P01-25 from Acris Antibodies
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TMED9 fusion protein - ag13754 from Proteintech Group
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TMED9 fusion protein - Ag13813 from Proteintech Group
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Human TMED9 Protein (His Tag) - 15056-H08H-20 from Sino Biological
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Human TMED9 Protein (Fc Tag) - 15056-H05H-20 from Sino Biological
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Recombinant human Transmembrane emp24 domain-containing protein 9 protein - CSB-EP048044h CSB-BP048044h CSB-MP048044h from Cusabio
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Recombinant Human Transmembrane emp24 domain-containing protein 9(TMED9) - CSB-YP880113HU CSB-EP880113HU CSB-BP880113HU CSB-MP880113HU from Cusabio
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Recombinant Human Transmembrane emp24 domain-containing protein 9(GP25L2) ,partial - CSB-RP048044h from Cusabio
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TMED9 - TP300652 from Acris Antibodies
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Recombinant Human TMED9 Protein, Fc-tagged - TMED9-642H from Creative Biomart
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Recombinant Human TMED9 Protein, His-tagged - TMED9-643H from Creative Biomart
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TMED9 Recombinant Protein Antigen - NBP1-83193PEP from Novus Biologicals
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TMED9 Peptide, Human - M34GP16063H from Creative Peptides
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Human TMED9 Protein (Fc Tag) - 15056-H05H from ABclonal
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Human TMED9 Protein (His Tag) - 15056-H08H from ABclonal
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Recombinant human Transmembrane emp24 domain-containing protein 9 - AP71858 from Signalway Antibody
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Protein P25, Recombinant Protein - MBS1344516 from MyBioSource
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