| Gene Symbol |
DFFB
|
| Entrez Gene |
1677
|
| Alt Symbol |
CAD, CPAN, DFF-40, DFF2, DFF40
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
|
| Other Description |
DNA fragmentation factor 40 kDa subunit|DNA fragmentation factor subunit beta|caspase-activated DNase|caspase-activated deoxyribonuclease|caspase-activated nuclease
|
| Swissprots |
Q9BYI4 O76075 Q5SR22 Q9BYI6 O60521 Q9BYI5
|
| Accessions |
EAW71485 EAW71486 EAW71487 EAW71488 EAW71489 EAW71490 EAW71491 O76075 AB013918 BAA32250 AB028911 BAB40447 AB028912 BAB40448 AB028913 BAB40449 AF039210 AAC39709 AF064019 AAC39920 AF409060 AAL02005 AF409061 AAL02006 AF409062 AAL02007 AK027141 AK290877 BAF83566 AK303065 BAG64182 AK309316 AY438267 AAR05821 AY438268 AAR05822 BC032827 AAH32827 BC048797 AAH48797 DC368011 XM_011540863 XP_011539165 XM_011540864 XP_011539166 XM_011540865 XP_011539167 XR_946563 XR_946564 XR_946565 NM_001282669 NP_001269598 NM_004402 NP_004393 NR_104222 NM_001004285 NM_001004286
|
| Function |
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Top Pathways |
Apoptosis
|