DFFB

Gene Symbol	DFFB
Entrez Gene	1677
Alt Symbol	CAD, CPAN, DFF-40, DFF2, DFF40
Species	Human
Gene Type	protein-coding
Description	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
Other Description	DNA fragmentation factor 40 kDa subunit|DNA fragmentation factor subunit beta|caspase-activated DNase|caspase-activated deoxyribonuclease|caspase-activated nuclease
Swissprots	Q9BYI4 O76075 Q5SR22 Q9BYI6 O60521 Q9BYI5
Accessions	EAW71485 EAW71486 EAW71487 EAW71488 EAW71489 EAW71490 EAW71491 O76075 AB013918 BAA32250 AB028911 BAB40447 AB028912 BAB40448 AB028913 BAB40449 AF039210 AAC39709 AF064019 AAC39920 AF409060 AAL02005 AF409061 AAL02006 AF409062 AAL02007 AK027141 AK290877 BAF83566 AK303065 BAG64182 AK309316 AY438267 AAR05821 AY438268 AAR05822 BC032827 AAH32827 BC048797 AAH48797 DC368011 XM_011540863 XP_011539165 XM_011540864 XP_011539166 XM_011540865 XP_011539167 XR_946563 XR_946564 XR_946565 NM_001282669 NP_001269598 NM_004402 NP_004393 NR_104222 NM_001004285 NM_001004286
Function	Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
Subcellular Location	Cytoplasm. Nucleus.
Top Pathways	Apoptosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CAD CRISPR/Cas9 KO Plasmid (h) - sc-403028 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD HDR Plasmid (h) - sc-403028-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD Double Nickase Plasmid (h) - sc-403028-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD Double Nickase Plasmid (h2) - sc-403028-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD CRISPR Activation Plasmid (h) - sc-403028-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD CRISPR Activation Plasmid (h2) - sc-403028-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD Lentiviral Activation Particles (h) - sc-403028-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD Lentiviral Activation Particles (h2) - sc-403028-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CAD siRNA (h) - sc-29871 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CAD shRNA Plasmid (h) - sc-29871-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CAD shRNA (h) Lentiviral Particles - sc-29871-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

DFF40/CAD RNAi - H00001677-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CAD RNAi - H00000790-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

DFF40/CAD RNAi - H00001677-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU100101 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7162 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7162 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10203 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10203

DFFB siRNA (Human) - CRH1186 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DFF40/CAD RNAi - H00001677-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

DFFB - MBS8225869 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human DFFB (NM_004402.2) - SHH277289 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human DFFB(NM_004402.2) - SHH002261 from Creative biogene Category siRNA Species Reactivities Human

Human DFFB siRNA - orb261688 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

DFFB shRNA Plasmid (Human) - CHH1186 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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