Gene Symbol | SIPA1L1 |
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Entrez Gene | 26037 |
Alt Symbol | E6TP1 |
Species | Human |
Gene Type | protein-coding |
Description | signal-induced proliferation-associated 1 like 1 |
Other Description | SIPA1-like protein 1|high-risk human papilloma viruses E6 oncoproteins targeted protein 1|signal-induced proliferation-associated 1-like protein 1 |
Swissprots | Q9UNU4 O95321 O43166 Q9UDU4 J3KP19 |
Accessions | AAC83179 CAD12684 CAD12685 CAD12686 CAD12687 CCA64007 CCA64575 EAW81058 EAW81059 EAW81060 O43166 AB007900 BAA23712 AF090989 AAD12543 AF090990 AAD12544 AK094532 AK122930 AK302650 BAG63889 BC033950 BC146777 AAI46778 CR936651 CAI56789 DA330003 XM_005267516 XP_005267573 XM_005267519 XP_005267576 XM_006720109 XP_006720172 XM_006720111 XP_006720174 XM_006720112 XP_006720175 XM_011536630 XP_011534932 XM_011536631 XP_011534933 XM_011536632 XP_011534934 XM_011536633 XP_011534935 XM_011536634 XP_011534936 XM_011536635 XP_011534937 XM_011536636 XP_011534938 XM_011536637 XP_011534939 XM_011536638 XP_011534940 XM_011536639 XP_011534941 NM_001284245 NP_001271174 NM_001284246 NP_001271175 NM_001284247 NP_001271176 NM_015556 NP_056371 |
Function | Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F- actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9858596}. |
Top Pathways | Rap1 signaling pathway |
E6TP1/Sipa1l1 (N-20) - sc-20846 from Santa Cruz Biotechnology
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E6TP1/Sipa1l1 (V-20) - sc-31615 from Santa Cruz Biotechnology
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E6TP1/Sipa1l1 (E-20) - sc-31616 from Santa Cruz Biotechnology
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Anti-SIPA1L1 antibody - ab91586 from Abcam
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Anti-SIPA1L1 antibody - ab113815 from Abcam
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Anti-E6TP1 / SIPA1L1 Antibody (N-Terminus) IHC-plus⢠- LS-B5053 from LifeSpan Bioscience
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SIPA1L1 Antibody - NBP1-90482 from Novus Biologicals
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Anti-SIPA1L1 antibody produced in rabbit - HPA002875 from Sigma-Aldrich
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Anti-SIPA1L1 antibody produced in rabbit - SAB3500248 from Sigma-Aldrich
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Anti-SIPA1L1 antibody produced in rabbit - SAB2900861 from Sigma-Aldrich
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SIPA1L1 antibody - orb75312 from Biorbyt
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SIPA1L1 antibody - 25086-1-AP from Acris Antibodies
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SIPA1L1 (N-term) antibody - AP23918PU-N from Acris Antibodies
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SIPA1L1 antibody - AP30781PU-N from Acris Antibodies
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Rabbit Anti-Human E6TP1 / SIPA1L1 (N-Terminus) - 119-14909 from RayBiotech
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SIPA1L1 Antibody - 5491 from ProSci
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SIPA1L1 antibody - 25086-1-AP from Proteintech Group
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SIPA1L1 Antibody - 254176 from ABBIOTEC
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SIPA1L1 Antibody - 25006 from Signalway Antibody
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Anti-SIPA1L1 (N-terminal) polyclonal antibody - DPAB-L21115 from Creative Diagnostics
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SIPA1L1 Polyclonal Antibody - PA5-20847 from Thermo Fisher Scientific
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E6TP1 / SIPA1L1, Polyclonal Antibody - MBS246962 from MyBioSource
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SIPA1L1, Polyclonal Antibody - MBS648408 from MyBioSource
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SIPA1L1, Polyclonal Antibody - MBS151262 from MyBioSource
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SIPA1L1 Antibody - 600-401-EL1 from Rockland Immunochemicals Inc
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