| Gene Symbol |
SIPA1L1
|
| Entrez Gene |
26037
|
| Alt Symbol |
E6TP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal-induced proliferation-associated 1 like 1
|
| Other Description |
SIPA1-like protein 1|high-risk human papilloma viruses E6 oncoproteins targeted protein 1|signal-induced proliferation-associated 1-like protein 1
|
| Swissprots |
Q9UNU4 O95321 O43166 Q9UDU4 J3KP19
|
| Accessions |
AAC83179 CAD12684 CAD12685 CAD12686 CAD12687 CCA64007 CCA64575 EAW81058 EAW81059 EAW81060 O43166 AB007900 BAA23712 AF090989 AAD12543 AF090990 AAD12544 AK094532 AK122930 AK302650 BAG63889 BC033950 BC146777 AAI46778 CR936651 CAI56789 DA330003 XM_005267516 XP_005267573 XM_005267519 XP_005267576 XM_006720109 XP_006720172 XM_006720111 XP_006720174 XM_006720112 XP_006720175 XM_011536630 XP_011534932 XM_011536631 XP_011534933 XM_011536632 XP_011534934 XM_011536633 XP_011534935 XM_011536634 XP_011534936 XM_011536635 XP_011534937 XM_011536636 XP_011534938 XM_011536637 XP_011534939 XM_011536638 XP_011534940 XM_011536639 XP_011534941 NM_001284245 NP_001271174 NM_001284246 NP_001271175 NM_001284247 NP_001271176 NM_015556 NP_056371
|
| Function |
Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F- actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Note=Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:9858596}.
|
| Top Pathways |
Rap1 signaling pathway
|
![Western Blot: SIPA1L1 Overexpression Lysate (Adult Normal) [NBP2-07149] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SIPA1L1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8639_SIPA1L1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07149-img0001.jpg)