Gene Symbol | Nrp1 |
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Entrez Gene | 18186 |
Alt Symbol | C530029I03, NP-1, NPN-1, Npn1, Nrp |
Species | Mouse |
Gene Type | protein-coding |
Description | neuropilin 1 |
Other Description | A5 protein|Neuropilin-1 precursor (A5 protein)|neuropilin-1|transmembrane receptor |
Swissprots | Q6PAR3 P97333 |
Accessions | AAP78928 CAI84569 CAM55895 EDL11827 EDL11828 P97333 AK002673 AK011144 AK030358 AK040447 AK082992 AK083052 AK135428 AK141964 BAE24901 AK148372 BAE28513 AK149752 AK159219 AK164378 AK171933 AK179138 AK188315 AK192303 AK207791 AK216801 BC006184 BC026730 BC032048 BC038657 BC051447 AAH51447 BC060129 AAH60129 D50086 BAA08789 XM_006530766 XP_006530829 XM_006530767 XP_006530830 XM_006530768 XP_006530831 NM_008737 NP_032763 |
Function | Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Nervous system. |
Top Pathways | Axon guidance, HTLV-I infection |
Recombinant Mouse Neuropilin-1, CF - 5994-N1-050 from R&D Systems
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Mouse Neuropilin 1 Protein - abx068257 from Abbexa
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Mouse Neuropilin 1 Protein - abx068263 from Abbexa
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Mouse Neuropilin 1 Protein - abx068264 from Abbexa
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Mouse Neuropilin 1 Protein - abx068262 from Abbexa
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Neuropilin 1 (NRP1), Mouse - 20-6989 from ARP American Research Products
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Neuropilin 1 (NRP1), Mouse - 20-6990 from ARP American Research Products
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Neuropilin 1 (NRP1), Mouse - 20-6991 from ARP American Research Products
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Neuropilin 1 (NRP1), Mouse - 20-6992 from ARP American Research Products
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Recombinant Mouse Nrp1, His-tagged - Nrp1-613M from Creative Biomart
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Recombinant Neuropilin 1 (NRP1) - RPA692Mu01 from Cloud-clone
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Recombinant Neuropilin 1 (NRP1) - RPA692Mu02 from Cloud-clone
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Recombinant Neuropilin 1 (NRP1) - RPA692Mu03 from Cloud-clone
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Recombinant Neuropilin 1 (NRP1) - RPA692Mu04 from Cloud-clone
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Recombinant Optineurin (OPTN) - RPC702Mu01 from Cloud-clone
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Recombinant Optineurin (OPTN) - RPC702Mu02 from Cloud-clone
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Recombinant Mouse Neuropilin-1(Nrp1) ,partial - CSB-YP016091MO CSB-EP016091MO CSB-BP016091MO CSB-MP016091MO from Cusabio
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Recombinant Mouse Neuropilin-1 Protein, CF - 5994-N1 from R&D Systems
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Neuropilin 1 (NRP1) - RPU143019 from Biomatik
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Neuropilin 1 (NRP1) - RPU143024 from Biomatik
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Neuropilin 1 (NRP1) - RPU143025 from Biomatik
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Neuropilin 1 (NRP1) - RPU143026 from Biomatik
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Neuropilin-1, Peptide - MBS843564 from MyBioSource
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Recombinant Mouse NRP1 Protein - NRP1-10898M from Creative Biomart
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Nrp1, 22-856aa, Mouse, His tag, Baculovirus - ATGP3360 from ATGen
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