Gene Symbol | Nrp1 |
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Entrez Gene | 18186 |
Alt Symbol | C530029I03, NP-1, NPN-1, Npn1, Nrp |
Species | Mouse |
Gene Type | protein-coding |
Description | neuropilin 1 |
Other Description | A5 protein|Neuropilin-1 precursor (A5 protein)|neuropilin-1|transmembrane receptor |
Swissprots | Q6PAR3 P97333 |
Accessions | AAP78928 CAI84569 CAM55895 EDL11827 EDL11828 P97333 AK002673 AK011144 AK030358 AK040447 AK082992 AK083052 AK135428 AK141964 BAE24901 AK148372 BAE28513 AK149752 AK159219 AK164378 AK171933 AK179138 AK188315 AK192303 AK207791 AK216801 BC006184 BC026730 BC032048 BC038657 BC051447 AAH51447 BC060129 AAH60129 D50086 BAA08789 XM_006530766 XP_006530829 XM_006530767 XP_006530830 XM_006530768 XP_006530831 NM_008737 NP_032763 |
Function | Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Nervous system. |
Top Pathways | Axon guidance, HTLV-I infection |
Neuropilin-1 Antibody - AF566 from Novus Biologicals
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Neuropilin-1 Antibody (761704) - MAB59941 from Novus Biologicals
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Neuropilin-1 Antibody (761705) - MAB5994 from Novus Biologicals
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Neuropilin-1 Antibody [Phycoerythrin] - FAB566P from Novus Biologicals
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Neuropilin-1 Antibody [Allophycocyanin] - FAB566A from Novus Biologicals
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Neuropilin-1 Antibody [PerCP (Peridinin-chlorophyll Protein Complex)] - FAB566C from Novus Biologicals
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Neuropilin-1 Antibody [Fluorescein] - FAB566F from Novus Biologicals
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Neuropilin-1 Antibody [Alexa Fluor 700] - FAB566N from Novus Biologicals
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Neuropilin-1 Antibody (761705) [Alexa Fluor 700] - FAB5994N from Novus Biologicals
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Neuropilin-1 Antibody (761705) [Alexa Fluor 488] - FAB5994G from Novus Biologicals
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Neuropilin-1 Antibody (761705) [Allophycocyanin] - FAB5994A from Novus Biologicals
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Neuropilin-1 Antibody (761705) [PE] - FAB5994P from Novus Biologicals
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Neuropilin 1 antibody - GTX127947 from GeneTex
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Neuropilin antibody - 10R-10590 from Fitzgerald
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Neuropilin 1 antibody - 70R-12148 from Fitzgerald
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Neuropilin 1 Antibody - abx101006 from Abbexa
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Neuropilin 1 Antibody - abx101007 from Abbexa
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Neuropilin 1 Antibody - abx101008 from Abbexa
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Neuropilin 1 Antibody - abx101009 from Abbexa
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Rabbit Anti-Neuropilin-1 Antibody - 168-10662 from RayBiotech
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APC anti-mouse CD304 (Neuropilin-1) Antibody - 145205 from Biolegend
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Brilliant Violet 421™ anti-mouse CD304 (Neuropilin-1) Antibody - 145209 from Biolegend
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PE anti-mouse CD304 (Neuropilin-1) Antibody - 145203 from Biolegend
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PE/Cy7 anti-mouse CD304 (Neuropilin-1) Antibody - 145211 from Biolegend
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PerCP/Cy5.5 anti-mouse CD304 (Neuropilin-1) Antibody - 145207 from Biolegend
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