FGD4

Gene Symbol FGD4
Entrez Gene 121512
Alt Symbol CMT4H, FRABP, ZFYVE6
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 4
Other Description FGD1 family, member 4|FGD1-related F-actin-binding protein|FYVE, RhoGEF and PH domain-containing protein 4|actin-filament binding protein frabin|zinc finger FYVE domain-containing protein 6
Swissprots Q6ULS2 Q96M96 Q8TCP6
Accessions CCQ43836 EAW88528 EAW88529 EAW88530 Q96M96 AK057294 BAB71413 AK091689 AK124654 AK297025 BAH12479 AK303334 BAH13945 AL713762 CAD28532 AL832064 AY367054 AAQ72372 BC039708 BC045552 AAH45552 BC063403 BC096746 BI756188 DA657803 DB446722 XM_005253304 XP_005253361 XM_005253307 XP_005253364 XM_005253308 XP_005253365 XM_005253309 XP_005253366 XM_005253310 XP_005253367 XM_011520554 XP_011518856 XM_011520555 XP_011518857 XM_011520556 XP_011518858 XM_011520557 XP_011518859 XM_011520558 XP_011518860 XM_011520559 XP_011518861 NM_001304480 NP_001291409 NM_001304481 NP_001291410 NM_001304483 NP_001291412 NM_001304484 NP_001291413 NM_139241 NP_640334
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Concentrated in filopodia and poorly detected at lamellipodia. Binds along the sides of actin fibers (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis. {ECO:0000269|PubMed:17564959}.

Frabin (H-74) - sc-366617 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Frabin (S-19) - sc-8596 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Frabin (S-19): sc-8596. Western blot analysis of Frabin expression in MOLT-4 whole cell lysate (A) and human uterus tissue extract (B).

Anti-FGD4 antibody - ab97785 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-FGD4 antibody (ab97785) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

Anti-FGD4 antibody - N-terminal - ab171309 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FGD4 antibody - N-terminal (ab171309) at 1/100 dilution + Human normal uterus tissue lysate at 35 µg

Anti-FGD4 Antibody (aa157-186, AP) - LS-C257211 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186, APC) - LS-C257212 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186, Biotin) - LS-C257213 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186, FITC) - LS-C257214 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186, Azide-free, HRP) - LS-C257215 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186, PE) - LS-C257216 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa156-186) - LS-C321361 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FGD4 Antibody (aa157-186) - LS-C166126 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FGD4 Antibody western blot of human normal Uterus tissue lysates (35 ug/lane). The FGD4 antibody detected the FGD4 protein (arrow).

Anti-FGD4 Antibody (aa49-327) - LS-C186104 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded SG xenograft using FGD4 antibody at 1:100 dilution.

FGD4 Antibody - NBP1-85532 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: FGD4 Antibody [NBP1-85532] - Immunofluorescent staining of human cell line U-2 OS shows localization to actin filaments.

FGD4 Antibody - NBP1-31335 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FGD4 Antibody [NBP1-31335] - Sample (30 ug of whole cell lysate) A: Molt-4 7.5% SDS PAGE, antibody diluted at 1:1000.

FGD4 Antibody - 36210002 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELISA: FGD4 Antibody [36210002]

Anti-FGD4 (182-195) antibody produced in rabbit - SAB1104186 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human FGD4 was separated on SDS-PAGE, blotted with Anti-FGD4 (182-195) (<B>Cat. No. SAB1104186</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + FGD4 immunizing peptide (human, 182-195)

Anti-FGD4 antibody produced in rabbit - HPA039235 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FGD4: <B>Cat. No. HPA039235</B>: Immunohistochemical staining of human testis shows distinct cytoplasmic positivity in cells in seminiferus ducts.

ANTI-FGD4 (N-TERM) antibody produced in rabbit - SAB1304240 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FGD4 (N-term): <B>Cat. No. SAB1304240</B>: FGD4 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35 μg/lane).

Anti-FGD4 antibody produced in rabbit - SAB2701052 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FGD4: <B>Cat. No. SAB2701052</B>: Immunohistochemical analysis of paraffin-embedded SG xenograft, using FGD4 antibody at 1:100 dilution.

FGD4-Antibody-N-term - AP12983a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
FGD4 Antibody (N-term) (Cat. #AP12983a) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the FGD4 antibody detected the FGD4 protein (arrow).

FGD4 antibody [N1N3] - GTX109859 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-FGD4 antibody [N1N3] used in ICC/IF. GTX109859

FGD4 Antibody - N-terminal region (OAAB09269) - OAAB09269 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

FGD4 antibody - orb74286 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa using FGD4 antibody
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