FGD4

Gene Symbol FGD4
Entrez Gene 121512
Alt Symbol CMT4H, FRABP, ZFYVE6
Species Human
Gene Type protein-coding
Description FYVE, RhoGEF and PH domain containing 4
Other Description FGD1 family, member 4|FGD1-related F-actin-binding protein|FYVE, RhoGEF and PH domain-containing protein 4|actin-filament binding protein frabin|zinc finger FYVE domain-containing protein 6
Swissprots Q6ULS2 Q96M96 Q8TCP6
Accessions CCQ43836 EAW88528 EAW88529 EAW88530 Q96M96 AK057294 BAB71413 AK091689 AK124654 AK297025 BAH12479 AK303334 BAH13945 AL713762 CAD28532 AL832064 AY367054 AAQ72372 BC039708 BC045552 AAH45552 BC063403 BC096746 BI756188 DA657803 DB446722 XM_005253304 XP_005253361 XM_005253307 XP_005253364 XM_005253308 XP_005253365 XM_005253309 XP_005253366 XM_005253310 XP_005253367 XM_011520554 XP_011518856 XM_011520555 XP_011518857 XM_011520556 XP_011518858 XM_011520557 XP_011518859 XM_011520558 XP_011518860 XM_011520559 XP_011518861 NM_001304480 NP_001291409 NM_001304481 NP_001291410 NM_001304483 NP_001291412 NM_001304484 NP_001291413 NM_139241 NP_640334
Function Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Note=Concentrated in filopodia and poorly detected at lamellipodia. Binds along the sides of actin fibers (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis. {ECO:0000269|PubMed:17564959}.

Frabin CRISPR/Cas9 KO Plasmid (h) - sc-410269 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin HDR Plasmid (h) - sc-410269-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin Double Nickase Plasmid (h) - sc-410269-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin Double Nickase Plasmid (h2) - sc-410269-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin CRISPR Activation Plasmid (h) - sc-410269-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin CRISPR Activation Plasmid (h2) - sc-410269-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin Lentiviral Activation Particles (h) - sc-410269-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin Lentiviral Activation Particles (h2) - sc-410269-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Frabin siRNA (h) - sc-41717 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Frabin shRNA Plasmid (h) - sc-41717-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Frabin shRNA (h) Lentiviral Particles - sc-41717-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FGD4 RNAi - H00121512-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU058211 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8642 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8642 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FGD4 siRNA (Human) - CRJ4677 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FGD4 - MBS8202136 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FGD4 (NM_139241.2) - SHH294325 from Creative biogene

Category siRNA
Species Reactivities Human

FGD4 shRNA Plasmid (Human) - CHJ4677 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more