Gene Symbol | DUSP4 |
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Entrez Gene | 1846 |
Alt Symbol | HVH2, MKP-2, MKP2, TYP |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 4 |
Other Description | MAP kinase phosphatase 2|VH1 homologous phosphatase 2|dual specificity protein phosphatase 4|dual specificity protein phosphatase hVH2|mitogen-activated protein kinase phosphatase 2|serine/threonine specific protein phosphatase |
Swissprots | Q13115 G5E930 Q13524 D3DSU4 B2RBU5 |
Accessions | EAW63481 EAW63482 EAW63483 EAW63484 Q13115 AI123616 AK314820 BAG37342 AL137704 BC002671 AAH02671 BC012900 BC014565 AAH14565 BG760517 BU742141 DA645190 EU831463 ACE87150 EU831550 ACE86469 S80632 AAB35870 U21108 AAA85119 U48807 AAC50452 XM_011544428 XP_011542730 NM_001394 NP_001385 NM_057158 NP_476499 |
Function | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
Subcellular Location | Nucleus. |
Top Pathways | MAPK signaling pathway |
DUSP4/MKP2 (D9A5) Rabbit mAb - 5149 from Cell Signaling Technology
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MKP-2 (F-10) - sc-17821 from Santa Cruz Biotechnology
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MKP-2 (H-67) - sc-10797 from Santa Cruz Biotechnology
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MKP-2 (N-14) - sc-74624 from Santa Cruz Biotechnology
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MKP-2 (S-18) - sc-1200 from Santa Cruz Biotechnology
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Anti-DUSP4 antibody - ab72593 from Abcam
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Anti-DUSP4 antibody - ab134286 from Abcam
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Anti-DUSP4 antibody - ab81774 from Abcam
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Anti-DUSP4 antibody - ab60229 from Abcam
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Anti-DUSP4 antibody - ab54937 from Abcam
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Anti-DUSP4 antibody [2295E1a] - ab53753 from Abcam
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Anti-DUSP4 antibody - C-terminal - ab135689 from Abcam
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Anti-DUSP4 / MKP2 Antibody - LS-C65053 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody - LS-C62164 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (clone 2295E1a) - LS-C184483 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, AP) - LS-C225205 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, APC) - LS-C225206 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, Biotin) - LS-C225207 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (aa76-125) - LS-C151621 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, FITC) - LS-C225208 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, PE) - LS-C225210 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (C-Terminus, Azide-free, HRP) - LS-C225209 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (AP) - LS-C225211 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (APC) - LS-C225212 from LifeSpan Bioscience
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Anti-DUSP4 / MKP2 Antibody (FITC) - LS-C225214 from LifeSpan Bioscience
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