Gene Symbol |
DUSP4
|
Entrez Gene |
1846
|
Alt Symbol |
HVH2, MKP-2, MKP2, TYP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
dual specificity phosphatase 4
|
Other Description |
MAP kinase phosphatase 2|VH1 homologous phosphatase 2|dual specificity protein phosphatase 4|dual specificity protein phosphatase hVH2|mitogen-activated protein kinase phosphatase 2|serine/threonine specific protein phosphatase
|
Swissprots |
Q13115 G5E930 Q13524 D3DSU4 B2RBU5
|
Accessions |
EAW63481 EAW63482 EAW63483 EAW63484 Q13115 AI123616 AK314820 BAG37342 AL137704 BC002671 AAH02671 BC012900 BC014565 AAH14565 BG760517 BU742141 DA645190 EU831463 ACE87150 EU831550 ACE86469 S80632 AAB35870 U21108 AAA85119 U48807 AAC50452 XM_011544428 XP_011542730 NM_001394 NP_001385 NM_057158 NP_476499
|
Function |
Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
|
Subcellular Location |
Nucleus.
|
Top Pathways |
MAPK signaling pathway
|