APOBEC3C

Gene Symbol APOBEC3C
Entrez Gene 27350
Alt Symbol A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Other Description DNA dC->dU-editing enzyme APOBEC-3C|apolipoprotein B editing enzyme catalytic polypeptide-like 3C|phorbolin I|probable DNA dC->dU-editing enzyme APOBEC-3C
Swissprots Q96F12 B2R884 Q5JZ92 Q7Z2N7 Q9NRW3
Accessions CAH05304 EAW60283 EAW60284 Q9NRW3 AB208979 BAD92216 AF165520 AAF86650 AK094570 AK313272 BAG36081 BC011739 AAH11739 BC021080 CR456394 CAG30280 CU012952 CAK54383 CU013240 CAK54682 KC329528 AGI04216 NM_014508 NP_055323
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the m
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:20308164}.

APOBEC3C (C-12) - sc-46731 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APOBEC3C (H-50) - sc-367880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
APOBEC3C (H-50): sc-367880. Western blot analysis of APOBEC3C expression in HEL 92.1.7 (A), AN3 CA (B) and U-937 (C) whole cell lysates.

APOBEC3C/D/F (N-13) - sc-46732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
APOBEC3C/D/F (N-13): sc-46732. Western blot analysis of APOBEC3C/D/F expression in Jurkat whole cell lysate.

Anti-APOBEC3C antibody - ab93377 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-APOBEC3C antibody (ab93377) at 1/1000 dilutionLane 1 : IM-9 cell lysate at 48 µgLane 2 : ECL cell lysate at 50 µg

Anti-APOBEC3C antibody - ab72652 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-APOBEC3C antibody (ab72652) at 1/500 dilutionLane 1 : APOBEC3C transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-APOBEC3C antibody - ab153953 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-APOBEC3C antibody (ab153953) at 1/2000 dilution + NCI-H929 whole cell lysate at 30 µg

Anti-APOBEC3C antibody [EPR13417] - ab181356 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13417
Flow cytometric analysis of permeabilized HeLa cells labeling APOBEC3C with ab181356 at 1/10 dilution (red) compared to a rabbit IgG negative control (green).

Anti-APOBEC3C antibody - C-terminal - ab199173 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-APOBEC3C antibody - C-terminal (ab199173) at 1/350 dilution + PC3 cell lysate at 40 µgdeveloped using the ECL technique

Anti-APOBEC3C antibody - C-terminal - ab77360 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-APOBEC3C antibody - C-terminal (ab77360) at 0.5 µg/ml + Daudi lysate at 35 µg

Anti-APOBEC3C Antibody - LS-C306291 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-APOBEC3C Antibody (aa91-191) - LS-C306295 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-APOBEC3C Antibody - LS-C309472 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3C Antibody - LS-C309473 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-APOBEC3C Antibody IHC-plus™ - LS-B11725 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-APOBEC3C Antibody - LS-C334357 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using APOBEC3C antibody.

Anti-APOBEC3C Antibody (aa201-212) - LS-C112640 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
APOBEC3C antibody (0.5 ug/ml) staining of Daudi lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APOBEC3C Antibody - NBP1-00131 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

APOBEC3C Antibody - NBP2-14875 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: APOBEC3C Antibody [NBP2-14875] - Sample (30 ug of whole cell lysate) A: NCI-H929 12% SDS PAGE, antibody diluted at 1:2000.

APOBEC3C Antibody - H00027350-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: APOBEC3C Antibody [H00027350-B01P] - Analysis of APOBEC3C expression in transfected 293T cell line by APOBEC3C polyclonal antibody. Lane 1: APOBEC3C transfected lysate(20.9 KDa). Lane 2: Non-transfected lysate.

APOBEC3C Antibody - H00027350-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: APOBEC3C Antibody [H00027350-D01P] - Analysis of APOBEC3C expression in transfected 293T cell line by APOBEC3C polyclonal antibody.Lane 1: APOBEC3C transfected lysate(22.80 KDa).Lane 2: Non-transfected lysate.

APOBEC3C Antibody - H00027350-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APOBEC3C Antibody (3E6) - H00027350-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E6

APOBEC3C Polyclonal Antibody - bs-12495R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APOBEC3C Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12495R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APOBEC3C Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12495R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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