APOBEC3C

Gene Symbol APOBEC3C
Entrez Gene 27350
Alt Symbol A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Other Description DNA dC->dU-editing enzyme APOBEC-3C|apolipoprotein B editing enzyme catalytic polypeptide-like 3C|phorbolin I|probable DNA dC->dU-editing enzyme APOBEC-3C
Swissprots Q96F12 B2R884 Q5JZ92 Q7Z2N7 Q9NRW3
Accessions CAH05304 EAW60283 EAW60284 Q9NRW3 AB208979 BAD92216 AF165520 AAF86650 AK094570 AK313272 BAG36081 BC011739 AAH11739 BC021080 CR456394 CAG30280 CU012952 CAK54383 CU013240 CAK54682 KC329528 AGI04216 NM_014508 NP_055323
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double- stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the m
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:20308164}.

Human APOBEC3C full length protein - ab162154 from Abcam

Category Protein
Prices $402.00
Sizes 2 µg
Source Wheat germ
Species Human
ab162154 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human APOBEC3C protein fragment - ab162155 from Abcam

Category Protein
Prices $402.00
Sizes 2 µg
Source Wheat germ
Species Human
ab162155 on a 12.5% SDS-PAGE stained with Coomassie Blue.

APOBEC3C Antibody Blocking Peptide - LS-E26599 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ARP5 / ANGPTL6 Antibody Blocking Peptide - LS-E9249 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human APOBEC3C Protein - H00027350-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human APOBEC3C Protein - H00027350-Q01 from Novus Biologicals

Category Protein
Prices $250.00
Sizes 2 µg
Source Wheat Germ
Species Human

APOBEC3C (C-term) blocking peptide - GTX88604-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

APOBEC3C blocking peptide - GTX88659-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

APOBEC3C Blocking Peptide - abx161018 from Abbexa

Category Peptide
Species Human, Rat

APOBEC3C - C-terminal Peptide - AC21-1435-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

APOBEC3C - H00027350-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

APOBEC3C - H00027350-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

APOBEC3C - H00027350-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

APOBEC3C Peptide - 42-743P from ProSci

Category Peptide
Species Human

APOBEC3C fusion protein - Ag0886 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human APOBEC3C, GST-tagged - APOBEC3C-9755H from Creative Biomart

Category Protein
Source E.coli
Species Human

APOBEC3C Blocking Peptide - CBP3517 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Rat

Recombinant Angiopoietin Like Protein 6 (ANGPTL6) - RPN468Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Probable DNA dC->dU-editing enzyme APOBEC-3C(APOBEC3C) - CSB-YP889097HU CSB-EP889097HU CSB-BP889097HU CSB-MP889097HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

APOBEC3C - TP303971 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
APOBEC3C

Probable DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C), Recombinant Protein - MBS1400886 from MyBioSource

Category Protein
Prices $935.00, $935.00, $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,855.00, $1,855.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Probable DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C), Recombinant Protein - MBS1310086 from MyBioSource

Category Protein
Prices $935.00, $935.00, $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,855.00, $1,855.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell

APOBEC3C, Peptide - MBS428427 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

APOBEC3C (C-term), Peptide - MBS425131 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

APOBEC3C-Antibody-C-term-Blocking-peptide - BP10252b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
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