CLEC4C

Gene Symbol	CLEC4C
Entrez Gene	170482
Alt Symbol	BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150
Species	Human
Gene Type	protein-coding
Description	C-type lectin domain family 4, member C
Other Description	BDCA-2|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11|C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 7|C-type lectin domain family 4 member C|C-type lectin superfamily member 7|blood dendritic cell antigen 2 protein|dendritic cell lectin b|dendritic lectin
Swissprots	Q8WXX8 Q6UXS8 Q8WTT0 Q3T1C3 D3DUU3
Accessions	EAW88654 EAW88655 EAW88656 Q8WTT0 AF293615 AAL37036 AF325459 AAL37358 AF325460 AAL37359 AK122596 BAG53616 AY358223 AAQ88590 BC074967 AAH74967 BC074968 AAH74968 BC102015 AAI02016 BC102016 AAI02017 BC102017 AAI02018 BC114338 AAI14339 NM_130441 NP_569708 NM_203503 NP_987099
Function	Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein- tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. {ECO:0000269|PubMed:11031109, ECO:0000269|PubMed:11748283}.
Subcellular Location	Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. {ECO:0000269|PubMed:11031109, ECO:0000269|PubMed:11536172, ECO:0000269|PubMed:11748283}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CLEC4C / CD303 / BDCA-2 Antibody Blocking Peptide - LS-E27058 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD303 blocking peptide - GTX88418-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Human CLEC4C Protein - abx066170 from Abbexa Category Protein Source E.coli Species Human

CLEC4C Peptide - AC21-1880-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CLEC4C Peptide - 42-155P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

CLEC4C fusion protein - ag12612 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CLEC4C fusion protein - Ag12363 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant C-Type Lectin Domain Family 4, Member C (CLEC4C) - RPB741Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant C-Type Lectin Domain Family 4, Member C (CLEC4C) - RPB741Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human C-type lectin domain family 4 member C(CLEC4C) - CSB-YP855470HU CSB-EP855470HU CSB-BP855470HU CSB-MP855470HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

C-Type Lectin Domain Family 4, Member C (CLEC4C) - RPU141046 from Biomatik Category Protein Prices $239.80, $479.60, $719.40 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

C-Type Lectin Domain Family 4, Recombinant Protein - MBS2031405 from MyBioSource Category Protein Prices $175.00, $370.00, $575.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

C-Type Lectin Domain Family 4, Recombinant Protein - MBS2029194 from MyBioSource Category Protein Prices $185.00, $390.00, $605.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

C-type lectin domain family 4 member C, Recombinant Protein - MBS1353819 from MyBioSource Category Protein Prices $110.00, $135.00, $190.00, $255.00, $285.00, $295.00, $420.00, $460.00, $575.00, $665.00, $750.00, $795.00, $915.00, $1,090.00, $1,180.00, $1,330.00, $1,725.00, $1,790.00, $2,620.00 Sizes 10 µg (E-Coli), 10 µg (Yeast), 50 µg (E-Coli), 50 µg (Yeast), 100 µg (E-Coli), 20 µg (Mammalian-Cell), 100 µg (Yeast), 200 µg (E-Coli), 50 µg (Mammalian-Cell), 200 µg (Yeast), 500 µg (E-Coli), 100 µg (Mammalian-Cell), 50 µg (Baculovirus), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

CLEC4C/BDCA2, Peptide - MBS425694 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human C-type lectin domain family 4 member C (CLEC4C) - CSB-MP855470HU from Cusabio Category Protein Source Mammalian cell Species Human

CLEC4C Peptide, Human - M34GP03268H from Creative Peptides Category Peptide Source Synthetic. Species Human

CLEC4C Recombinant Protein (OPCA02435) - OPCA02435 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

CLEC4C Recombinant Protein (OPCA03671) - OPCA03671 from Aviva Systems Biology Category Protein Prices $445.00 Sizes 20 µg Source Human

Human CLEC4C protein - orb358925 from Biorbyt Category Protein Prices $459.00, $816.00, $1,131.00 Sizes 20 μg, 50 μg, 100 μg Species Human

Recombinant C-Type Lectin Domain Family 4, Member C (CLEC4C) - RPU41046 from Biomatik Category Protein Prices $192.00, $392.00, $600.00, $715.04 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

CLEC4C Recombinant Protein (OPCD02255) - OPCD02255 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human DLEC/CLEC4C/BDCA-2 Fc Chimera Protein, CF - 1376-DL from R&D Systems Category Protein Prices $319.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human IgG 1 (Ser102-Lys330) IEGR Human DLEC (Phe46-Ile213) Accession # Q8WTT0 N-terminus C-terminus Species Human

Recombinant Human C-type lectin domain family 4 member C(CLEC4C),partial - AP74577 from Signalway Antibody Category Protein Prices $155.00, $390.00, $665.00, $1,090.00, $1,835.00, $2,915.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Recombinant Human C-type lectin domain family 4 member C (CLEC4C) ,partial - AP74663 from Signalway Antibody Category Protein Prices $469.00, $940.00, $1,310.00 Sizes 20 µg, 50 µg, 100 µg Source Mammalian cell Species Human

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