Gene Symbol | ARHGDIG |
---|---|
Entrez Gene | 398 |
Alt Symbol | RHOGDI-3 |
Species | Human |
Gene Type | protein-coding |
Description | Rho GDP dissociation inhibitor (GDI) gamma |
Other Description | RhoGDI gamma|rho GDI 3|rho GDP-dissociation inhibitor 3|rho-GDI gamma |
Swissprots | Q99819 Q96S29 Q4TT69 |
Accessions | AAC72354 AAK61222 CAI95584 CAI95585 CAM26353 EAW85837 Q99819 AB593111 BAJ84051 AF498928 AAM21076 BC047699 AAH47699 BM662457 BU732723 U82532 AAC33138 NM_001176 NP_001167 |
Function | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Primarily expressed in pancreas and brain. |
Top Pathways | Neurotrophin signaling pathway, Vasopressin-regulated water reabsorption |
Rho GDIγ CRISPR/Cas9 KO Plasmid (h) - sc-406401 from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ HDR Plasmid (h) - sc-406401-HDR from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ Double Nickase Plasmid (h) - sc-406401-NIC from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ Double Nickase Plasmid (h2) - sc-406401-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ CRISPR Activation Plasmid (h) - sc-406401-ACT from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ CRISPR Activation Plasmid (h2) - sc-406401-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ Lentiviral Activation Particles (h) - sc-406401-LAC from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ Lentiviral Activation Particles (h2) - sc-406401-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ siRNA (h) - sc-41877 from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ shRNA Plasmid (h) - sc-41877-SH from Santa Cruz Biotechnology
|
||||||||
Rho GDIγ shRNA (h) Lentiviral Particles - sc-41877-V from Santa Cruz Biotechnology
|
||||||||
ARHGDIG RNAi - H00000398-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU219931 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3440 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3440 from Sigma-Aldrich
|
||||||||
ARHGDIG siRNA (Human) - CRH0287 from Cohesion Biosciences
|
||||||||
ARHGDIG - MBS8221294 from MyBioSource
|
||||||||
shRNA set against Human ARHGDIG (NM_001176.3) - SHH239665 from Creative biogene
|
||||||||
Human ARHGDIG siRNA - orb260789 from Biorbyt
|
||||||||
ARHGDIG shRNA Plasmid (Human) - CHH0287 from Cohesion Biosciences
|