Gene Symbol | ARHGDIG |
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Entrez Gene | 398 |
Alt Symbol | RHOGDI-3 |
Species | Human |
Gene Type | protein-coding |
Description | Rho GDP dissociation inhibitor (GDI) gamma |
Other Description | RhoGDI gamma|rho GDI 3|rho GDP-dissociation inhibitor 3|rho-GDI gamma |
Swissprots | Q99819 Q96S29 Q4TT69 |
Accessions | AAC72354 AAK61222 CAI95584 CAI95585 CAM26353 EAW85837 Q99819 AB593111 BAJ84051 AF498928 AAM21076 BC047699 AAH47699 BM662457 BU732723 U82532 AAC33138 NM_001176 NP_001167 |
Function | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Primarily expressed in pancreas and brain. |
Top Pathways | Neurotrophin signaling pathway, Vasopressin-regulated water reabsorption |
Rho GDIγ (E-1) - sc-393690 from Santa Cruz Biotechnology
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Rho GDIγ (H-95) - sc-367757 from Santa Cruz Biotechnology
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Rho GDIγ (M-95) - sc-367756 from Santa Cruz Biotechnology
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Rho GDIγ (N-19) - sc-6910 from Santa Cruz Biotechnology
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Anti-ARHGDIG antibody - ab157493 from Abcam
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Anti-ARHGDIG antibody - ab54841 from Abcam
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Anti-ARHGDIG / RHOGDI-3 Antibody (aa176-221) - LS-C313922 from LifeSpan Bioscience
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Anti-ARHGDIG / RHOGDI-3 Antibody (aa42-90) - LS-C29749 from LifeSpan Bioscience
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Anti-ARHGDIG / RHOGDI-3 Antibody (clone 1D11) - LS-C196693 from LifeSpan Bioscience
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Anti-ARHGDIG / RHOGDI-3 Antibody (aa27-205) - LS-C179140 from LifeSpan Bioscience
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Anti-ARHGDIG / RHOGDI-3 Antibody (aa43-54) IHC-plus⢠- LS-B8339 from LifeSpan Bioscience
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ARHGDIG Antibody - H00000398-B01 from Novus Biologicals
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ARHGDIG Antibody - NBP1-49854 from Novus Biologicals
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ARHGDIG Antibody - NBP1-59112 from Novus Biologicals
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ARHGDIG Antibody - H00000398-A01 from Novus Biologicals
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ARHGDIG Antibody (1D11) - H00000398-M01 from Novus Biologicals
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Anti-ARHGDIG antibody produced in rabbit - HPA053974 from Sigma-Aldrich
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Anti-ARHGDIG antibody produced in rabbit - AV33854 from Sigma-Aldrich
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Anti-ARHGDIG (C-terminal) antibody produced in goat - SAB2501409 from Sigma-Aldrich
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Monoclonal Anti-ARHGDIG antibody produced in mouse - WH0000398M1 from Sigma-Aldrich
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ARHGDIG antibody - N-terminal region (ARP33854_P050) - ARP33854_P050 from Aviva Systems Biology
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ARHGDIG-Antibody-C-Term - AF3282a from Abgent, a WuXi AppTec company
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ARHGDIG antibody, C-term - GTX88058 from GeneTex
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Anti -ARHGDIG (RHOGDI-3, RhoGDI gamma, Rho GDP dissociation inhibitor [GDI] gamma) - R1998-24 from USBiological Life Science
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Anti -ARHGDIG (RHOGDI-3, RhoGDI gamma, Rho GDP dissociation inhibitor [GDI] gamma) - 123499 from USBiological Life Science
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