GHR

Gene Symbol GHR
Entrez Gene 2690
Alt Symbol GHBP, GHIP
Species Human
Gene Type protein-coding
Description growth hormone receptor
Other Description GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor
Swissprots Q9HCX2 P10912
Accessions AAA52555 AAB34503 AAF71399 CAC06613 CAC06615 CAH05763 CAM36317 CBJ05777 CBJ21229 CDM63320 EAW56023 P10912 AF230800 AF230801 BC136496 AAI36497 BM719293 BU625645 S97393 AAD15015 X06562 CAA29808 Z11801 CAA77845 Z11802 CAA77846 Z11848 CAA77872 Z11849 CAA77873 Z11850 CAA77874 Z11851 CAA77875 Z11853 CAA77877 XM_011514031 XP_011512333 NM_000163 NP_000154 NM_001242399 NP_001229328 NM_001242400 NP_001229329 NM_001242401 NP_001229330 NM_001242402 NP_001229331 NM_001242403 NP_001229332 NM_001242404 NP_001229333 NM_001242405 NP_001229334 NM_001242406 NP_001229335 NM_001242460 NP_001229389 NM_001242462 NP_001229391 NM_001242461
Function Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Subcellular Location Growth hormone-binding protein: Secreted. Note=Complexed to a substantial fraction of circulating GH. {ECO:0000250}.
Tissue Specificity Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform 1 expression in placenta is predominant in chorion and decidua. Isoform 4 is highly expressed in placental villi. Isoform 2 is expressed in lung, stomach and muscle. Low levels in liver.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction

GHR CRISPR/Cas9 KO Plasmid (h) - sc-401382 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR HDR Plasmid (h) - sc-401382-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR Double Nickase Plasmid (h) - sc-401382-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR Double Nickase Plasmid (h2) - sc-401382-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR CRISPR Activation Plasmid (h) - sc-401382-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR CRISPR Activation Plasmid (h2) - sc-401382-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR Lentiviral Activation Particles (h) - sc-401382-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR Lentiviral Activation Particles (h2) - sc-401382-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GHR siRNA (h) - sc-40015 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GHR shRNA Plasmid (h) - sc-40015-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GHR shRNA (h) Lentiviral Particles - sc-40015-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Growth Hormone R RNAi - H00002690-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU060521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9275 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9275 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GHR siRNA (Human) - CRH1793 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GHR - MBS8229259 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Ghr (NM_000163.4) - SHH300966 from Creative biogene

Category siRNA
Species Reactivities Human

Human GHR siRNA - orb262295 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GHR shRNA Plasmid (Human) - CHH1793 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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