GHR

Gene Symbol	GHR
Entrez Gene	2690
Alt Symbol	GHBP, GHIP
Species	Human
Gene Type	protein-coding
Description	growth hormone receptor
Other Description	GH receptor|growth hormone binding protein|serum binding protein|somatotropin receptor
Swissprots	Q9HCX2 P10912
Accessions	AAA52555 AAB34503 AAF71399 CAC06613 CAC06615 CAH05763 CAM36317 CBJ05777 CBJ21229 CDM63320 EAW56023 P10912 AF230800 AF230801 BC136496 AAI36497 BM719293 BU625645 S97393 AAD15015 X06562 CAA29808 Z11801 CAA77845 Z11802 CAA77846 Z11848 CAA77872 Z11849 CAA77873 Z11850 CAA77874 Z11851 CAA77875 Z11853 CAA77877 XM_011514031 XP_011512333 NM_000163 NP_000154 NM_001242399 NP_001229328 NM_001242400 NP_001229329 NM_001242401 NP_001229330 NM_001242402 NP_001229331 NM_001242403 NP_001229332 NM_001242404 NP_001229333 NM_001242405 NP_001229334 NM_001242406 NP_001229335 NM_001242460 NP_001229389 NM_001242462 NP_001229391 NM_001242461
Function	Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Subcellular Location	Growth hormone-binding protein: Secreted. Note=Complexed to a substantial fraction of circulating GH. {ECO:0000250}.
Tissue Specificity	Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. Isoform 1 expression in placenta is predominant in chorion and decidua. Isoform 4 is highly expressed in placental villi. Isoform 2 is expressed in lung, stomach and muscle. Low levels in liver.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Growth hormone receptor protein fragment - ab180053 from Abcam Category Protein Prices $357.00 Sizes 50 µg Source HEK 293 cells Species Human

Active human Growth hormone receptor protein fragment - ab180056 from Abcam Category Protein Prices $357.00 Sizes 50 µg Source HEK 293 cells Species Human

Active human Growth hormone receptor protein fragment - ab68380 from Abcam Category Protein Prices $192.00 Sizes 20 µg Source E. coli Species Human

Cow Growth hormone receptor protein fragment - ab68383 from Abcam Category Protein Source E. coli Species Bovine

Human Growth hormone receptor peptide - ab73395 from Abcam Category Peptide

Human Growth hormone receptor protein fragment - ab179965 from Abcam Category Protein Source HEK 293 cells Species Human

Growth hormone receptor protein (Fc Chimera) - ab83991 from Abcam Category Protein Source Baculovirus Species Human

GHBP / BLVRB Antibody Blocking Peptide - LS-E20321 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Growth Hormone Receptor / GHR Antibody Blocking Peptide - LS-E16248 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Growth Hormone R Partial Recombinant Protein - H00002690-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Growth Hormone R Recombinant Protein - P4172 from Novus Biologicals Category Protein Prices $669.00 Sizes 50 µg Species Human

Recombinant Human Growth Hormone R Protein - NBP1-99906 from Novus Biologicals Category Protein Prices $305.00 Sizes 50 µg Source E. coli Species Human

GHR-Antibody-N-term-Blocking-Peptide - BP16661a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GHBP (Active) recombinant protein - GTX65106 from GeneTex Category Protein Prices $369.00 Sizes 50 μg Source E. coli Species Human

Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF - 1210-GR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Mouse Growth Hormone R (GHR) Fc Chimera, CF - 1360-GR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

GHBP Protein (OPPA00503) - OPPA00503 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human GHBP protein - orb80351 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

GHBP protein - 30R-2794 from Fitzgerald Category Protein Prices $425.00 Sizes 50 µg Source E.coli Species Human

GHR Blocking Peptide - 33R-5341 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human GHR Protein - abx066957 from Abbexa Category Protein Source E.coli Species Human

Growth hormone receptor - H00002690-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Growth hormone receptor - H00002690-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Growth hormone receptor - P4172 from Acris Antibodies Category Protein Prices $670.00 Sizes 50 µg Species Human

Growth Hormone Binding Protein, Human Recombinant - 228-10543-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

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