Gene Symbol | PKP3 |
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Entrez Gene | 11187 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | plakophilin 3 |
Other Description | plakophilin 3b|plakophilin-3 |
Swissprots | Q53EX8 Q9Y446 F8J390 |
Accessions | EAX02322 EAX02323 Q9Y446 AF053719 AAF23050 AK025067 AK223511 BAD97231 BC000081 AAH00081 BG611119 BX356582 CA947983 DB139782 DQ891692 ABM82618 DQ894875 ABM85801 FN421477 CAZ65731 Z98265 CAB44310 NM_001303029 NP_001289958 NM_007183 NP_009114 |
Function | May play a role in junctional plaques. |
Subcellular Location | Nucleus. Cell junction, desmosome. Note=Nuclear and associated with desmosomes. |
Tissue Specificity | Isoform PKP3a is found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues. Isoform PKP3b is abundant in the desmosomes of stratified epithelial cell but absent in simple epithelial cells, it is also expressed in the colon and its tumors. {ECO:0000269|PubMed:24178805}. |
Plakophilin 3 (PKP3), ELISA Kit - MBS9313095 from MyBioSource
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Plakophilin 3 (PKP3), ELISA Kit - MBS9302665 from MyBioSource
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Plakophilin 3 (PKP3), ELISA Kit - MBS9303447 from MyBioSource
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Plakophilin-3, ELISA Kit - MBS282045 from MyBioSource
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Human PKP3 ELISA Kit - E029553 from Biobool
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