Gene Symbol |
NUBP1
|
Entrez Gene |
4682
|
Alt Symbol |
NBP, NBP1, NBP35
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nucleotide binding protein 1
|
Other Description |
NBP 1|cytosolic Fe-S cluster assembly factor NUBP1|nucleotide binding protein (e.coli MinD like)|nucleotide binding protein 1 (E.coli MinD like)|nucleotide binding protein 1 (MinD homolog, E. coli)|nucleotide-binding protein 1
|
Swissprots |
Q498A9 Q32M30 P53384 Q53FS7
|
Accessions |
EAW85178 P53384 AK223204 BAD96924 AK307148 AK310089 BC100290 AAI00291 BC109322 AAI09323 BC109323 AAI09324 BP216107 BP225034 U01833 AAA61932 XM_006720886 XP_006720949 NM_001278506 NP_001265435 NM_002484 NP_002475
|
Function |
Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000250, ECO:0000269|PubMed:18573874}.
|
Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03038, ECO:0000269|PubMed:18573874}.
|