Gene Symbol | NUBP1 |
---|---|
Entrez Gene | 4682 |
Alt Symbol | NBP, NBP1, NBP35 |
Species | Human |
Gene Type | protein-coding |
Description | nucleotide binding protein 1 |
Other Description | NBP 1|cytosolic Fe-S cluster assembly factor NUBP1|nucleotide binding protein (e.coli MinD like)|nucleotide binding protein 1 (E.coli MinD like)|nucleotide binding protein 1 (MinD homolog, E. coli)|nucleotide-binding protein 1 |
Swissprots | Q498A9 Q32M30 P53384 Q53FS7 |
Accessions | EAW85178 P53384 AK223204 BAD96924 AK307148 AK310089 BC100290 AAI00291 BC109322 AAI09323 BC109323 AAI09324 BP216107 BP225034 U01833 AAA61932 XM_006720886 XP_006720949 NM_001278506 NP_001265435 NM_002484 NP_002475 |
Function | Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000250, ECO:0000269|PubMed:18573874}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03038, ECO:0000269|PubMed:18573874}. |