Gene Symbol | NUBP1 |
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Entrez Gene | 4682 |
Alt Symbol | NBP, NBP1, NBP35 |
Species | Human |
Gene Type | protein-coding |
Description | nucleotide binding protein 1 |
Other Description | NBP 1|cytosolic Fe-S cluster assembly factor NUBP1|nucleotide binding protein (e.coli MinD like)|nucleotide binding protein 1 (E.coli MinD like)|nucleotide binding protein 1 (MinD homolog, E. coli)|nucleotide-binding protein 1 |
Swissprots | Q498A9 Q32M30 P53384 Q53FS7 |
Accessions | EAW85178 P53384 AK223204 BAD96924 AK307148 AK310089 BC100290 AAI00291 BC109322 AAI09323 BC109323 AAI09324 BP216107 BP225034 U01833 AAA61932 XM_006720886 XP_006720949 NM_001278506 NP_001265435 NM_002484 NP_002475 |
Function | Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000250, ECO:0000269|PubMed:18573874}. |
Subcellular Location | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03038, ECO:0000269|PubMed:18573874}. |
NUBP1 CRISPR/Cas9 KO Plasmid (h) - sc-410896 from Santa Cruz Biotechnology
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NUBP1 HDR Plasmid (h) - sc-410896-HDR from Santa Cruz Biotechnology
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NUBP1 Double Nickase Plasmid (h) - sc-410896-NIC from Santa Cruz Biotechnology
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NUBP1 Double Nickase Plasmid (h2) - sc-410896-NIC-2 from Santa Cruz Biotechnology
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NUBP1 CRISPR Activation Plasmid (h) - sc-410896-ACT from Santa Cruz Biotechnology
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NUBP1 CRISPR Activation Plasmid (h2) - sc-410896-ACT-2 from Santa Cruz Biotechnology
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NUBP1 Lentiviral Activation Particles (h) - sc-410896-LAC from Santa Cruz Biotechnology
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NUBP1 Lentiviral Activation Particles (h2) - sc-410896-LAC-2 from Santa Cruz Biotechnology
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NUBP1 siRNA (h) - sc-93202 from Santa Cruz Biotechnology
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NUBP1 shRNA Plasmid (h) - sc-93202-SH from Santa Cruz Biotechnology
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NUBP1 shRNA (h) Lentiviral Particles - sc-93202-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15577 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15577 from Sigma-Aldrich
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NUBP1 siRNA (Human) - CRH3098 from Cohesion Biosciences
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shRNA set against Human NUBP1 (NM_002484.2) - SHH355888 from Creative biogene
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shRNA set against Human NUBP1(NM_002484.2) - SHR024846 from Creative biogene
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Human NUBP1 siRNA - orb263600 from Biorbyt
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NUBP1 shRNA Plasmid (Human) - CHH3098 from Cohesion Biosciences
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NUBP1 miRNA 3'UTR clone - MiUTR1H-06957 from Creative biogene
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