KPNA6

Gene Symbol KPNA6
Entrez Gene 23633
Alt Symbol IPOA7, KPNA7
Species Human
Gene Type protein-coding
Description karyopherin alpha 6 (importin alpha 7)
Other Description importin alpha 7 subunit|importin subunit alpha-7|importin-alpha-S2|karyopherin subunit alpha-6
Swissprots Q5VVU3 B2RDC7 D3DPP5 O60684
Accessions EAX07567 EAX07568 EAX07569 O60684 AB621806 BAK64142 AF060543 AAC15233 AK000724 AK002111 AK128609 AK295615 BAG58497 AK301714 BAG63185 AK315490 BAG37874 AU142228 BC020520 AAH20520 BP374991 BT009843 AAP88845 DQ891587 ABM82513 DQ894781 ABM85707 XM_005270711 XP_005270768 XM_011541160 XP_011539462 NM_012316 NP_036448
Function Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. {ECO:0000269|PubMed:10523667}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10523667}.

karyopherin α6 (C-12) - sc-68197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

karyopherin α6 (H-54) - sc-292794 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
karyopherin α6 (H-54): sc-292794. Western blot analysis of karyopherin α6 expression in non-transfected: sc-110760 (A) and human karyopherin α6 transfected: sc-113217 (B) 293T whole cell lysates.

karyopherin α6 (E-11) - sc-390055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
karyopherin α6 (E-11): sc-390055. Western blot analysis of karyopherin α6 expression in HeLa (A), K-562 (B), Hep G2 (C), Caki-1 (D), ES-2 (E) and HuT 78 (F) whole cell lysates.

Anti-KPNA6 antibody - ab110016 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab110016, at 3.75 µg/ml, staining KPNA6 in Human adrenal tissue by immunohistochemistry.

Anti-KPNA6 antibody - ab82149 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-KPNA6 antibody (ab82149) at 0.1 µg/ml + human skeletal muscle lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-KPNA6 antibody - ab105350 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KPNA6 antibody (ab105350) at 1 µg/ml + 293 cell lysate at 15 µg

Anti-KPNA6 antibody - ab104977 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KPNA6 antibody (ab104977) at 1 µg/ml + Human fetal brain lysate at 10 µg

Anti-KPNA6 Antibody (aa74-123) - LS-C81952 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-KPNA6 Antibody (N-Terminus) - LS-C115912 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of KPNA6 in 293 cells with KPNA6 antibody at 20 ug/ml.

Anti-KPNA6 Antibody (aa74-87) IHC-plus™ - LS-B4460 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-KPNA6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4460 concentration 3.75 ug/ml.

KPNA6 Antibody - NBP1-83762 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KPNA6 Antibody - NB100-93456 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: KPNA6 Antibody [NB100-93456] - (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

KPNA6 Antibody - NBP1-52953 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

KPNA7 Antibody - NBP1-91014 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KPNA6 antibody produced in rabbit - SAB2101295 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KPNA6: <B>Cat. No.SAB2101295</B>: KPNA6 in Fetal Brain tissue lysate with KPNA6 antibody at 1.0 μg/mL.

Anti-KPNA7 antibody produced in rabbit - SAB3500792 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry </B><BR/>KPNA7 Antibody: <B>Cat. No. SAB3500792</B>: Immunohistochemistry of KPNA7 in Human placenta tissue with KPNA7 antibody at 5 μg/mL.

Anti-KPNA6 antibody produced in rabbit - HPA018863 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KPNA6: <B>Cat. No. HPA018863</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong nuclear positivity in cells in tubules and cells in glomeruli.

Anti-KPNA6 antibody produced in goat - SAB2500576 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KPNA6: <B>Cat. No. SAB2500576</B>: (0.1 μg/mL) staining of Human Muscle lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-KPNA6 antibody produced in rabbit - SAB3500563 from Sigma-Aldrich

Prices $346.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KPNA6: <B>Cat. No. SAB3500563</B>: KPNA6 in 293 cell lysate with KPNA6 antibody at 1 μg/mL.

KPNA6 antibody - N-terminal region (ARP54879_P050) - ARP54879_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KPNA6-Antibody - AF1605a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1605a (0.1 µg/ml) staining of Human Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

KPNA6 antibody, N-term - GTX49108 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

KPNA6 antibody, Internal - GTX88712 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-KPNA6 antibody, Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX88712

KPNA6 antibody - orb75501 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of 293 cell lysate at 1 ug/mL using KPNA6 antibody

KPNA7 antibody - orb75758 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed and paraffin-embedded human placenta tissue at 5 ug/mL using KPNA7 antibody
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