KPNA6

Gene Symbol KPNA6
Entrez Gene 23633
Alt Symbol IPOA7, KPNA7
Species Human
Gene Type protein-coding
Description karyopherin alpha 6 (importin alpha 7)
Other Description importin alpha 7 subunit|importin subunit alpha-7|importin-alpha-S2|karyopherin subunit alpha-6
Swissprots Q5VVU3 B2RDC7 D3DPP5 O60684
Accessions EAX07567 EAX07568 EAX07569 O60684 AB621806 BAK64142 AF060543 AAC15233 AK000724 AK002111 AK128609 AK295615 BAG58497 AK301714 BAG63185 AK315490 BAG37874 AU142228 BC020520 AAH20520 BP374991 BT009843 AAP88845 DQ891587 ABM82513 DQ894781 ABM85707 XM_005270711 XP_005270768 XM_011541160 XP_011539462 NM_012316 NP_036448
Function Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. {ECO:0000269|PubMed:10523667}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10523667}.

Human KPNA6 full length protein - ab161726 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161726 on a 12.5% SDS-PAGE stained with Coomassie Blue.

KPNA6 Antibody Blocking Peptide - LS-E31007 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

KPNA6 Antibody Blocking Peptide - LS-E26717 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KPNA6 Antibody Blocking Peptide - LS-E19788 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KPNA7 Antibody Blocking Peptide - LS-E31008 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

KPNA7 Antibody Blocking Peptide - LS-E24328 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

KPNA6 Recombinant Protein - H00023633-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

KPNA6 Peptide - NBP1-76301PEP from Novus Biologicals

Category Peptide
Prices $149.00
Sizes 50 µg
Species Human

KPNA6-Antibody-C-term-Blocking-peptide - BP12228b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KPNA6 blocking peptide - GTX88712-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat, Bovine

KPNA6 Peptide - AC21-1556-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

KPNA6 / Importin alpha-7 - H00023633-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

KPNA6 / Importin alpha-7 - H00023633-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

KPNA6 / Importin alpha-7 control peptide - AP26277CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

KPNA6 / Importin alpha-7 (N-term) Control Peptide - AP55453CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

KPNA6 Peptide - 46-860P from ProSci

Category Peptide
Species Human

KPNA6 Peptide - 5991P from ProSci

Category Peptide
Species Human

KPNA6 fusion protein - Ag3040 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human Importin subunit alpha-7(KPNA6) - CSB-YP012488HU CSB-EP012488HU CSB-BP012488HU CSB-MP012488HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

KPNA6 Protein - abx164042 from Abbexa

Category Protein
Species Human, Mouse

KPNA6 / Importin alpha-7 - TP303926 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
KPNA6 / Importin alpha-7

KPNA6, Peptide - MBS425068 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Pig, Bovine

KPNA7 Recombinant Protein Antigen - NBP1-91014PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KPNA6 Recombinant Protein Antigen - NBP1-83762PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

KPNA6 Peptide, Human - M34GP08341H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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