KIF5A

Gene Symbol KIF5A
Entrez Gene 3798
Alt Symbol D12S1889, MY050, NKHC, SPG10
Species Human
Gene Type protein-coding
Description kinesin family member 5A
Other Description KIF5A variant protein|kinesin heavy chain isoform 5A|kinesin heavy chain neuron-specific 1|kinesin, heavy chain, neuron-specific|neuronal kinesin heavy chain
Swissprots A6H8M5 Q4LE26 Q12840
Accessions EAW97030 Q12840 AB210045 BAE06127 AB290174 BAG06728 AF063608 AAG43166 AK294881 BAH11913 AK315202 BAG37640 AL118561 AL707807 BC033961 BC035285 BC051752 BC140009 AAI40010 BC146670 AAI46671 BC150208 AAI50209 BM930000 U06698 AAA20231 NM_004984 NP_004975
Function Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). {ECO:0000250}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Concentrated in the cell body of the neurons, particularly in the perinuclear region. {ECO:0000250}.
Tissue Specificity Distributed throughout the CNS but is highly enriched in subsets of neurons.
Top Pathways Dopaminergic synapse

NKHC1 (C-11) - sc-376452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NKHC1 (C-11): sc-376452. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing cytoplasmic staining of glandular cells.

NKHC1 (D-3) - sc-398759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NKHC1 (D-3): sc-398759. Western blot analysis of NKHC1 expression in non-transfected: sc-117752 (A) and human NKHC1 transfected: sc-112832 (B) 293T whole cell lysates.

NKHC1 (G-1) - sc-374666 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NKHC1 (G-1): sc-374666. Western blot analysis of NKHC1 expression in IMR-32 whole cell lysate.

NKHC1 (G-20) - sc-13353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of neuronal kinesin heavy chain expression in SH-SY5Y whole cell lysate. Antibodies tested include NKHC1 (N-17): sc-13351 (A) and NKHC1 (G-20): sc-13353 (B).

NKHC1 (H-75) - sc-25734 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NKHC1 (H-75): sc-25734. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebral cortex tissue showing nuclear and cytoplasmic staining of neuronal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

NKHC1 (N-17) - sc-13351 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of neuronal kinesin heavy chain expression in SH-SY5Y whole cell lysate. Antibodies tested include NKHC1 (N-17): sc-13351 (A) and NKHC1 (G-20): sc-13353 (B).

Anti-Kinesin 5 A + B + C antibody - ab62104 from Abcam

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Kinesin 5 A + B + C antibody (ab62104) at 0.5 µg/mlLane 2 : Anti-Kinesin 5 A + B + C antibody (ab62104) at 1 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate

Anti-Kinesin 5 A + B + C antibody - ab62105 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Kinesin 5 A + B + C antibody (ab62105) at 0.5 µg/mlLane 2 : Anti-Kinesin 5 A + B + C antibody (ab62105) at 1 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate

Anti-Kinesin 5A antibody - ab118534 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cortex tissue (formalin-fixed, paraffin-embedded) stained with ab118534 at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Kinesin 5A antibody - C-terminal - ab154414 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of methanol-fixed HeLa cells, labeling Kinesin 5A using ab154414 at a 1/500 dilution.

Anti-Kinesin 5A / KIF5A Antibody (Internal) IHC-plus™ - LS-B2714 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIF5A antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2714 concentration 5 ug/ml.

Anti-Kinesin 5A / KIF5A Antibody (aa1007-1027) - LS-C71378 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa1019-1032) - LS-C55031 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa473-605, Biotin) - LS-C298475 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa2-211, Biotin) - LS-C299962 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa823-1027, Biotin) - LS-C301040 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa473-605, FITC) - LS-C301835 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa2-211, FITC) - LS-C302530 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa823-1027, FITC) - LS-C302947 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa657-706) - LS-C30431 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIF5A antibody LS-C30431 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-Kinesin 5A / KIF5A Antibody (aa473-605) - LS-C295041 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Kinesin 5A / KIF5A.

Anti-Kinesin 5A / KIF5A Antibody - LS-C335325 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Kinesin 5A / KIF5A Antibody (aa823-1027) - LS-C295044 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Kinesin 5A / KIF5A.

Anti-Kinesin 5A / KIF5A Antibody (aa2-211) - LS-C295043 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Kinesin 5A / KIF5A.

Anti-Kinesin 5A / KIF5A Antibody (aa982-1032) - LS-C290981 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human KIF5A by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-KIF5A antibody used for IP at 6 ug per reaction. KIF5A was also immunoprecipitated by rabbit anti-KIF5A antibody BL16263. For blotting immunoprecipitated KIF5A, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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