ATG14

Gene Symbol ATG14
Entrez Gene 22863
Alt Symbol ATG14L, BARKOR, KIAA0831
Species Human
Gene Type protein-coding
Description autophagy related 14
Other Description ATG14 autophagy related 14 homolog|Beclin 1-Interacting protein|autophagy-related protein 14-like protein|beclin 1-associated autophagy-related key regulator
Swissprots B7ZWP5 Q32MK8 O94920 A8K9U5 Q32MK7 A6NJE4 Q6ZNE5
Accessions CBX47442 EAW80672 EAW80673 EAW80674 Q6ZNE5 AA988343 AK131251 BAD18430 AK292810 BAF85499 AL049978 BC028015 BC109089 AAI09090 BC109090 AAI09091 BR000826 FAA00433 XM_011536563 XP_011534865 XM_011536564 XP_011534866 NM_014924 NP_055739
Function Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (By similarity). {ECO:0000250|UniProtKB:Q8CDJ3, ECO:0000269|PubMed:18843052, ECO:0000269|PubMed:19050071, ECO:0000269|PubMed:19270696, ECO:0000269|PubMed:20713597, ECO:0000269|PubMed:23878393}.
Subcellular Location Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein. Note=Cytosolic under nutrient-rich conditions. Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes. Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). {ECO:0000250}.
Top Pathways Regulation of autophagy

KIAA0831, ELISA Kit - MBS9317079 from MyBioSource

Category ELISA Kit
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Human KIAA0831 ELISA Kit - E021675 from Biobool

Category ELISA Kit

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9346591 from MyBioSource

Category ELISA Kit
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Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9358443 from MyBioSource

Category ELISA Kit
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Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9359686 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9359075 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9354462 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9350987 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9352102 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9364822 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9359289 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9360352 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9367980 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9368367 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9361711 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9343454 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9351642 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9359861 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9371436 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9350355 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9361466 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9366514 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beclin-1-Associated Autophagy Related Key Regulator (Barkor), ELISA Kit - MBS9359222 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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