LTA

Gene Symbol LTA
Entrez Gene 4049
Alt Symbol LT, TNFB, TNFSF1
Species Human
Gene Type protein-coding
Description lymphotoxin alpha
Other Description LT-alpha|TNF superfamily, member 1|TNF-beta|lymphotoxin-alpha|tumor necrosis factor beta|tumor necrosis factor ligand superfamily member 1
Swissprots Q8N4C3 Q9UKS8 P01374
Accessions AAA61199 AAB59455 AAD18092 AAL49956 AAO21135 AAP51421 AAP51422 AAP51423 AAP51424 AAP51425 AAP51426 AAP51427 AAP51428 AAP51429 AAP51430 AAP51431 AAP51432 AAP51433 AAP51434 AAP51435 AAP51436 AAP51437 AAP51438 AAP51439 AAP51440 AAP51441 AAP51442 AAP51443 AAP51444 ACA64643 ACA64644 ACA64645 ACA64646 AHH34316 AHH34317 AHH34318 AHH34319 AHH34320 AHH34321 AHH34322 AHH34323 AHH34324 AHI45173 AHI45174 AHI45175 AHI45176 BAB63397 BAC54943 BAE78638 BAF31278 CAA26670 CAA75071 CAA78746 CAI95949 EAX03422 EAX03423 P01374 A06316 CAA00536 BC034729 AAH34729 BG685356 BP338937 BX108399 CR542253 CAG47049 CR542273 CAG47069 D00102 BAA00064 D12614 BAA02139 DQ123821 AAZ32914 DQ123822 AAZ32915 DQ123823 AAZ32916 DQ123824 AAZ32917 DQ123825 AAZ32918 DQ123826 AAZ32919 DQ123827 AAZ32920 DQ891119 ABM82045 DQ894298 ABM85224 X01393 CAA25649 XM_011514614 XP_011512916 XM_011514615 XP_011512917 XM_011514616 XP_011512918 XM_011514617 XP_011512919 XM_011514618 XP_011512920 XM_011547250 XP_011545552 XM_011547653 XP_011545955 XM_011547654 XP_011545956 XM_011547883 XP_011546185 XM_011547884 XP_011546186 XM_011547885 XP_011546187 XM_011547886 XP_011546188 XM_011547887 XP_011546189 XM_011548050 XP_011546352 XM_011548051 XP_011546353 XM_011548242 XP_011546544 XM_011548243 XP_011546545 XM_011548436 XP_011546738 XM_011548437 XP_011546739 XM_011548438 XP_011546740 XM_011548439 XP_011546741 XM_011548440 XP_011546742 NM_000595 NP_000586 NM_001159740 NP_001153212
Function Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Subcellular Location Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated.
Top Pathways Cytokine-cytokine receptor interaction, Type I diabetes mellitus, HTLV-I infection, Herpes simplex infection, TNF signaling pathway

TNFβ (359-81-11) - sc-32767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of purified human recombinant TNFβ immunoprecipitated with TNFβ (359-81-11): sc-32767 and detected with TNFβ (C-20): sc-1352.

TNFβ (D-10) - sc-48410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TNFβ (D-10): sc-48410. Western blot analysis of human recombinant TNFβ.

TNFβ (E-6) - sc-28345 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TNFβ (E-6): sc-28345. Western blot analysis of human recombinant TNFβ.

TNFβ (H-171) - sc-8302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TNFβ (H-171): sc-8302. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic and membrane staining of cells in seminiferous ducts and cytoplasmic staining of Leydig cells.

TNFβ (N-20) - sc-1354 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TNFβ (N-20): sc-1354. Western blot analysis of human recombinant TNFβ.

TNFβ (R-20) - sc-1353 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TNFβ (R-20): sc-1353. Western blot analysis of human recombinant TNFβ (A,B).

TNFβ (C-20) - sc-1352 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of human recombinant TNFβ (A,B). Antibodies tested include TNFβ (C-20): sc-1352 (A) and TNFβ (R-20): sc-1353 (B).

Anti-Lymphotoxin Alpha + Beta antibody [MM0460-12B4] - ab89566 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone MM0460-12B4
ab89566 staining Lymphotoxin Alpha + Beta in PBMC, T cell progenitors by Flow Cytometry. The sample was incubated with the primary antibody (1/50 in 1X PBS) for 15 minutes at 4°C. A Alexa Fluor® -conjugated donkey anti-mouse IgG (1/20) was used as the secondary antibody.Gating Strategy: CD7+ cells.See Abreview

Anti-TNF beta antibody - ab197677 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed paraffin embedded human colon cancer tissue labeling TNF beta with ab197677 at a 1/50 dilution.

Anti-TNF beta antibody - ab106353 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TNF beta antibody (ab106353) at 1 µg/mlLane 1 : Recombinant Human TNF beta protein at 20ngLane 2 : Recombinant Human TNF beta protein at 5ngLane 3 : Recombinant Human TNF beta protein at 2.5ng

Anti-TNF beta antibody - ab10951 from Abcam

Prices $370.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-TNF beta antibody - ab136015 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TNF beta antibody (ab136015) at 1/500 dilution + COS-7 cell lysate at 30 µg

Anti-TNF beta antibody - ab167123 from Abcam

Host Sheep
Clonality Polyclonal

Anti-TNF beta antibody [359-81-11] (Allophycocyanin) - ab95625 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 359-81-11

Anti-TNF beta antibody [359-81-11] (Phycoerythrin) - ab93517 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 359-81-11
Staining of Th1 polarized human peripheral blood cells with FITC anti-human CD4, followed by fixation, permeabilization and intracellular staining with 0.125 µg of ab93517 (right) or Phycoerythrin Mouse IgG1, K Iso Control (left). Total viable cells were used for analysis.

Anti-TNF beta antibody [AT15A3] - ab100844 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone AT15A3
IHC image of ab100844 staining in human skin melanoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab100844, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-TNF beta antibody (Biotin) - ab12787 from Abcam

Prices $359.00
Sizes 25 µg
Host Rabbit
Clonality Polyclonal

Anti-TNF beta antibody [EP1113Y] - ab52639 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1113Y
Anti-TNF beta antibody [EP1113Y] (ab52639) at 1/5000 dilution + Recombinant TNF beta at 0.05 µgSecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-LTA / Lipoteichoic Acid Antibody - LS-C102920 from LifeSpan Bioscience

Prices $320.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LTA / Lipoteichoic Acid Antibody - LS-C102921 from LifeSpan Bioscience

Prices $320.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LTA / Lipoteichoic Acid Antibody (clone 55) - LS-C202488 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 55

Anti-LTA / TNF Beta Antibody - LS-C18312 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LTA / TNF Beta Antibody (FITC) - LS-C18338 from LifeSpan Bioscience

Prices $560.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-LTA / TNF Beta Antibody - LS-C48872 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LTA / TNF Beta Antibody (clone 359-81-11) - LS-C41027 from LifeSpan Bioscience

Prices $215.00, $295.00
Sizes 50 µg, 500 µg
Host Mouse
Clonality Monoclonal
Clone 359-81-11
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