Gene Symbol | VPS53 |
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Entrez Gene | 55275 |
Alt Symbol | HCCS1, PCH2E, hVps53L, pp13624 |
Species | Human |
Gene Type | protein-coding |
Description | vacuolar protein sorting 53 homolog (S. cerevisiae) |
Other Description | vacuolar protein sorting-associated protein 53 homolog |
Swissprots | Q8WYW3 Q9NV25 B3FH42 A8K2S8 Q9BY02 Q9BRR2 Q5VIR6 |
Accessions | EAW90658 EAW90659 EAW90660 EAW90661 EAW90662 Q5VIR6 AF085927 AF246287 AAK27973 AF318335 AAL55842 AK001841 BAA91935 AK056323 AK057942 AK091388 AK092532 BAG52568 AK123107 AK290343 BAF83032 AK299543 BAH13062 AL701573 AY444797 AAS20944 BC006116 AAH06116 BC029560 AAH29560 BC039432 BC040223 CB851054 EU021218 ABW03005 EU434648 ACA21423 EU434649 ACA21424 EU434650 ACA21425 XM_011523953 XP_011522255 XR_934061 XR_934062 NM_001128159 NP_001121631 NM_018289 NP_060759 |
Function | May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. {ECO:0000269|PubMed:15878329, ECO:0000269|PubMed:18367545}. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. |
VPS53 (H-174) - sc-383034 from Santa Cruz Biotechnology
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VPS53 (L-13) - sc-109143 from Santa Cruz Biotechnology
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VPS53 (N-16) - sc-109144 from Santa Cruz Biotechnology
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Anti-VPS53 antibody - ab106469 from Abcam
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Anti-VPS53 antibody - ab69422 from Abcam
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Anti-HCCS1 / VPS53 Antibody (aa111-140) - LS-C160543 from LifeSpan Bioscience
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Anti-HCCS1 / VPS53 Antibody (C-Terminus) - LS-C53295 from LifeSpan Bioscience
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Anti-HCCS1 / VPS53 Antibody (Internal) - LS-C53296 from LifeSpan Bioscience
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Anti-HCCS1 / VPS53 Antibody (aa431-480) - LS-C108094 from LifeSpan Bioscience
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VPS53 Antibody - NBP1-76901 from Novus Biologicals
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VPS53 Antibody - NBP1-83799 from Novus Biologicals
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VPS53 Antibody - NBP1-83798 from Novus Biologicals
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VPS53 Antibody - H00055275-B01P from Novus Biologicals
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Anti-VPS53 antibody produced in rabbit - SAB3500320 from Sigma-Aldrich
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Anti-VPS53 antibody produced in rabbit - HPA022988 from Sigma-Aldrich
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Anti-VPS53 antibody produced in rabbit - HPA024446 from Sigma-Aldrich
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VPS53 antibody - middle region (ARP57192_P050) - ARP57192_P050 from Aviva Systems Biology
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VPS53-Antibody-N-term - AP8546a from Abgent, a WuXi AppTec company
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VPS53 Antibody - N-terminal region (OAAB05138) - OAAB05138 from Aviva Systems Biology
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VPS53 antibody - orb74984 from Biorbyt
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VPS53 antibody - orb74985 from Biorbyt
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VPS53 antibody - 70R-21276 from Fitzgerald
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VPS53 Polyclonal Antibody - A4821 from ABclonal
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VPS53 antibody - 70R-3481 from Fitzgerald
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VPS53 Antibody - abx036229 from Abbexa
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