Gene Symbol | AGPAT5 |
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Entrez Gene | 55326 |
Alt Symbol | 1AGPAT5, LPAATE |
Species | Human |
Gene Type | protein-coding |
Description | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
Other Description | 1-AGP acyltransferase 5|1-AGPAT 5|1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon|1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)|lysophosphatidic acid acyltransferase epsilon |
Swissprots | Q9NUQ2 Q8IZ47 Q9BQG4 |
Accessions | CAH05435 CAH05479 EAW80476 EAW80477 EAW80478 Q9NUQ2 AF375789 AAK54809 AK002072 BAA92069 AK021722 AK310545 AL136587 CAB66522 AL514578 AM392899 CAL37777 AM393058 CAL37936 BC023550 AAH23550 BC068519 AAH68519 BC080537 AAH80537 BM837881 CA414711 DQ893436 ABM84362 DQ896747 ABM87746 XM_011534751 XP_011533053 NM_018361 NP_060831 |
Function | Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable. {ECO:0000269|PubMed:21173190}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21173190}; Multi-pass membrane protein {ECO:0000269|PubMed:21173190}. Nucleus envelope {ECO:0000269|PubMed:21173190}. Mitochondrion {ECO:0000269|PubMed:21173190}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:21173190}. |
Top Pathways | Glycerolipid metabolism, Glycerophospholipid metabolism |
Anti-AGPAT5 antibody - ab135912 from Abcam
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Anti-AGPAT5 antibody - ab69430 from Abcam
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Anti-AGPAT5 antibody [1D4] - ab119366 from Abcam
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Anti-AGPAT5 Antibody - LS-C306138 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, Azide-free, HRP) - LS-C249393 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa27-54) - LS-C319375 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 4H3) - LS-C337597 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 1D4) - LS-C173661 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 1H10) - LS-C173662 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 1D12) - LS-C173688 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 2C4) - LS-C173664 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, AP) - LS-C232505 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, Biotin) - LS-C232507 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa36-85) - LS-C81055 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa241-290) - LS-C119603 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, FITC) - LS-C232509 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa231-280) - LS-C200103 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, APC) - LS-C232506 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55, PE) - LS-C232510 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody - LS-C155738 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (clone 5F4) - LS-C173663 from LifeSpan Bioscience
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Anti-AGPAT5 Antibody (aa28-55) - LS-C161019 from LifeSpan Bioscience
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AGPAT5 Antibody (2C4) - NBP2-01664 from Novus Biologicals
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AGPAT5 Antibody - NBP2-15306 from Novus Biologicals
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AGPAT5 Antibody - H00055326-B01P from Novus Biologicals
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