AGPAT5

Gene Symbol AGPAT5
Entrez Gene 55326
Alt Symbol 1AGPAT5, LPAATE
Species Human
Gene Type protein-coding
Description 1-acylglycerol-3-phosphate O-acyltransferase 5
Other Description 1-AGP acyltransferase 5|1-AGPAT 5|1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon|1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)|lysophosphatidic acid acyltransferase epsilon
Swissprots Q9NUQ2 Q8IZ47 Q9BQG4
Accessions CAH05435 CAH05479 EAW80476 EAW80477 EAW80478 Q9NUQ2 AF375789 AAK54809 AK002072 BAA92069 AK021722 AK310545 AL136587 CAB66522 AL514578 AM392899 CAL37777 AM393058 CAL37936 BC023550 AAH23550 BC068519 AAH68519 BC080537 AAH80537 BM837881 CA414711 DQ893436 ABM84362 DQ896747 ABM87746 XM_011534751 XP_011533053 NM_018361 NP_060831
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable. {ECO:0000269|PubMed:21173190}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:21173190}; Multi-pass membrane protein {ECO:0000269|PubMed:21173190}. Nucleus envelope {ECO:0000269|PubMed:21173190}. Mitochondrion {ECO:0000269|PubMed:21173190}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:21173190}.
Top Pathways Glycerolipid metabolism, Glycerophospholipid metabolism

LPAAT-ε siRNA (h) - sc-77618 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPAAT-ε shRNA Plasmid (h) - sc-77618-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPAAT-ε shRNA (h) Lentiviral Particles - sc-77618-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU036011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2952 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2952 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGPAT5 siRNA (Human) - CRJ0658 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGPAT5 - MBS8200093 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human AGPAT5 siRNA - orb271159 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGPAT5 shRNA Plasmid (Human) - CHJ0658 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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