| Gene Symbol |
Pdcd1
|
| Entrez Gene |
18566
|
| Alt Symbol |
Ly101, PD-1, Pdc1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
programmed cell death 1
|
| Other Description |
mPD-1|programmed cell death protein 1|protein PD-1
|
| Swissprots |
Q02242
|
| Accessions |
EDL39922 Q02242 AK039828 BAC30463 BC119179 AAI19180 BC120602 AAI20603 X67914 CAA48113 NM_008798 NP_032824
|
| Function |
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Thymus.
|
| Top Pathways |
T cell receptor signaling pathway, Cell adhesion molecules (CAMs)
|