Pdcd1

Gene Symbol Pdcd1
Entrez Gene 18566
Alt Symbol Ly101, PD-1, Pdc1
Species Mouse
Gene Type protein-coding
Description programmed cell death 1
Other Description mPD-1|programmed cell death protein 1|protein PD-1
Swissprots Q02242
Accessions EDL39922 Q02242 AK039828 BAC30463 BC119179 AAI19180 BC120602 AAI20603 X67914 CAA48113 NM_008798 NP_032824
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Thymus.
Top Pathways T cell receptor signaling pathway, Cell adhesion molecules (CAMs)

The plasmid was transfected into 293H adherent cells with Sinofection reagent (Cat# STF01). After 48 h, Immunofluorescence staining of cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Flag Tag monoclonal antibody (CST#8146S) at 37℃ 1 hour. Then cells were stained with Goat Anti-mouse IgG secondary antibody. The fluorescent signal is detected by fluorescence microscope. Each expression experiment has negative control.

Mouse Pdcd1 ORF Clone(NM_008798.2) - CDCR246148 from Creative biogene

Species Mouse

Mouse PDCD1 ORF clone (NM_008798.1) - CDCB157215 from Creative biogene

Species Mouse
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