PON2

Gene Symbol PON2
Entrez Gene 5445
Alt Symbol -
Species Human
Gene Type protein-coding
Description paraoxonase 2
Other Description A-esterase 2|PON 2|aromatic esterase 2|arylesterase 2|paraoxonase nirs|serum aryldialkylphosphatase 2|serum paraoxonase/arylesterase 2
Swissprots A4D1H7 O75856 Q86YL0 B4DJD5 O15114 Q15165 B2RCP9 Q5FBX7 O15115
Accessions AAC27946 AAC62431 AAO18083 EAL24131 EAW76763 EAW76764 EAW76765 EAW76766 EAW76767 Q15165 AB102891 BAD89420 AF001601 AAC27944 AF001602 AAC27945 AK054688 AK291103 BAF83792 AK296029 BAG58797 AK296636 BAG59238 AK301313 BAG62864 AK308065 AK315209 BAG37646 BC009728 AAH09728 BC040010 AAH40010 BC046160 AAH46160 BC073739 BC093006 CB961097 L48513 AAC41995 XM_005250453 XP_005250510 XM_005250454 XP_005250511 XM_011516333 XP_011514635 NM_000305 NP_000296 NM_001018161 NP_001018171
Function Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. {ECO:0000269|PubMed:11579088, ECO:0000269|PubMed:15772423}.
Subcellular Location Membrane {ECO:0000269|PubMed:11579088}; Peripheral membrane protein {ECO:0000269|PubMed:11579088}.
Tissue Specificity Widely expressed with highest expression in liver, lung, placenta, testis and heart. {ECO:0000269|PubMed:11579088}.

PON2 (C-5) - sc-374158 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PON2 (C-5): sc-374158. Western blot analysis of PON2 expression in HeLa (A) and Hep G2 (B) whole cell lysates.

PON2 (D-12) - sc-373981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PON2 (D-12): sc-373981. Western blot analysis of PON2 expression in HeLa (A) and Hep G2 (B) whole cell lysates.

PON2 (C-13 ) - sc-66578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PON2 antibody - ab175496 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PON2 antibody (ab175496) at 1/1000 dilution + HepG2 cell line lysates at 15 µg

Anti-PON2 antibody - ab157517 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PON2 antibody (ab157517) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysate

Anti-PON2 antibody [AF3E6] - ab85340 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AF3E6
Overlay histogram showing HepG2 cells stained with ab85340 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab85340, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H+L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG ( 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-PON2 antibody [EPR15295] - ab183710 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15295
All lanes : Anti-PON2 antibody [EPR15295] (ab183710) at 1/20000 dilutionLane 1 : HeLa cell lysateLane 2 : HepG2 cell lysateLane 3 : A431 cell lysateLane 4 : U87-MG cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-PON2 antibody [EPR15295-58] - ab183718 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15295-58
All lanes : Anti-PON2 antibody [EPR15295-58] (ab183718) at 1/1000 dilutionLane 1 : HeLa whole cell lysateLane 2 : U87-MG whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PON2 Antibody (aa79-107) IHC-plus™ - LS-B10154 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-PON2 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PON2 Antibody (aa93-103) IHC-plus™ - LS-B8315 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PON2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8315 dilution 3.75 ug/ml.

Anti-PON2 Antibody (aa30-354) - LS-C38070 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PON2 Antibody (aa30-354) - LS-C126112 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-PON2 Antibody (Internal) - LS-C145014 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody - LS-C51601 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Lane 1: Marker Lane 2: 50 ug Mouse brain tissue lysate Primary antibody: 4 ug/ml Rabbit Anti-PON2 Polyclonal Antibody LS-C51601 Lane 3: 50 ug Mouse brain tissue lysate Primary antibody: 2 ug/ml Rabbit Anti-PON2 Polyclonal Antibody LS-C51601 Lane 4: 50 ug Mouse brain tissue lysate Primary antibody: 1 ug/ml Rabbit Anti-PON2 Polyclonal Antibody LS-C51601 Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody

Anti-PON2 Antibody - LS-C154773 from LifeSpan Bioscience

Prices $295.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody - LS-C192866 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using PON2 antibody.

Anti-PON2 Antibody (aa74-101, AP) - LS-C266718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa74-101, APC) - LS-C266720 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa74-101, Biotin) - LS-C266721 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa42-177) - LS-C179183 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa74-101, FITC) - LS-C266722 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa74-101, Azide-free, HRP) - LS-C266723 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa74-101, PE) - LS-C266724 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa78-107, AP) - LS-C266725 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PON2 Antibody (aa78-107, Biotin) - LS-C266726 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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