CYP7A1

Gene Symbol	CYP7A1
Entrez Gene	1581
Alt Symbol	CP7A, CYP7, CYPVII
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 7, subfamily A, polypeptide 1
Other Description	cholesterol 7-alpha-hydroxylase\|cholesterol 7-alpha-monooxygenase\|cytochrome P450 7A1\|cytochrome P450, subfamily VIIA polypeptide 1
Swissprots	Q7KZ19 P22680 P78454 Q3MIL8
Accessions	AAA58423 AAA61350 EAW86811 P22680 BC101777 AAI01778 BC112184 AAI12185 M93133 AAA58435 X56088 CAA39568 XM_011517476 XP_011515778 NM_000780 NP_000771
Function	Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. {ECO:0000269\|PubMed:19965590}.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity	Detected in liver. {ECO:0000269\|PubMed:15796896}.
Top Pathways	Primary bile acid biosynthesis, Steroid hormone biosynthesis, PPAR signaling pathway, Bile secretion

CYP7A1 (C-20) - sc-14426 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CYP7A1 (C-20): sc-14426. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

CYP7A1 (H-58) - sc-25536 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

CYP7A1 (H-58): sc-25536. Western blot analysis of CYP7A1 expression in BxPC-3 (A), U-251-MG (B), Hep G2 (C), HeLa (D), K-562 (E) and Jurkat (F) whole cell lysates.

CYP7A1 (N-17) - sc-14423 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-CYP7A1 antibody - ab65596 from Abcam

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 antibody - C-terminal - ab79847 from Abcam

Prices	$382.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 antibody - C-terminal (ab79847) at 1/50 dilution + K562 cell lysates at 35 µg

Anti-CYP7A1 Antibody (aa227-467, Biotin) - LS-C298970 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 Antibody (C-Terminus) - LS-C99807 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of CYP7A1 Antibody in K562(lane 1), HepG2(lane 2) cell line lysates (35 ug/lane). CYP7A1 (arrow) was detected using the purified antibody.

Anti-CYP7A1 Antibody (aa227-467, FITC) - LS-C302506 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 Antibody (aa252-504) - LS-C311660 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 Antibody (aa227-467) - LS-C294116 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 Antibody (aa109-383) - LS-C314683 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 Antibody (aa194-208) - LS-C313076 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

CYP7A1 antibody. IHC(P): Human Liver Cancer Tissue.

CYP7A1 Polyclonal Antibody - bs-2399R from Bioss

Prices	$279.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Mouse liver lysates probed with Anti-CYP7A1 Polyclonal Antibody, Unconjugated (bs-2399R) at 1:300 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 90min in 37˚C

ANTI-CYP7A1 (C-TERM) antibody produced in rabbit - SAB1304995 from Sigma-Aldrich

Prices	$326.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-CYP7A1 (C-term): <B>Cat. No. SAB1304995</B>: Western blot analysis of CYP7A1 Antibody (C-term) in cell line lysates (35 μg/lane).<BR/><B>Lanes:</B><BR/>1. K562<BR/>2. HepG2

Anti-CYP7A1 antibody produced in rabbit - SAB4301212 from Sigma-Aldrich

Prices	$230.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CYP7A1-Antibody-C-term - AP7996a from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of CYP7A1 Antibody (C-term) (Cat.#AP7996a) in K562(lane 1), HepG2(lane 2) cell line lysates (35ug/lane). CYP7A1 (arrow) was detected using the purified Pab.

CYP7A1 Antibody - C-terminal region (OAAB05044) - OAAB05044 from Aviva Systems Biology

Prices	$289.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

CYP7A1 antibody [N3C3] - GTX108871 from GeneTex

Prices	$149.00
Sizes	100 μl
Host	Rabbit
Clonality	Polyclonal

CYP7A1 antibody, C-term - GTX81230 from GeneTex

Prices	$319.00
Sizes	400 μl
Host	Rabbit
Clonality	Polyclonal

Anti-CYP7A1 antibody, C-term used in Western blot. GTX81230

CYP7A1 antibody - orb5022 from Biorbyt

Prices	$60.00, $128.00, $255.00, $340.00
Sizes	5 μg (Trial size), 20 μg (Trial size), 100 μg, 200 μg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of rat brain lysates(30ug), rat kidney lysates(30ug) using CYP7A1 antibody

CYP7A1 Antibody (OABF00958) - OABF00958 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti -CYP7A1 (CYPVII, Cholesterol 7-alpha-hydroxylase, Cytochrome P450 7A1) - 144429 from USBiological Life Science

Host	Rabbit
Clonality	Polyclonal

CYP7A1 antibody - orb97066 from Biorbyt

Prices	$340.00
Sizes	100 μg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of Lane 1: HELA Cell Lysate, Lane 2: 293T Cell Lysate, Lane 3: JURKAT Cell Lysate using CYP7A1 antibody

CYP7A1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-2399R-A350 from Bioss

Prices	$379.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CYP7A1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-2399R-A488 from Bioss

Prices	$379.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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