CYP7A1

Gene Symbol CYP7A1
Entrez Gene 1581
Alt Symbol CP7A, CYP7, CYPVII
Species Human
Gene Type protein-coding
Description cytochrome P450, family 7, subfamily A, polypeptide 1
Other Description cholesterol 7-alpha-hydroxylase|cholesterol 7-alpha-monooxygenase|cytochrome P450 7A1|cytochrome P450, subfamily VIIA polypeptide 1
Swissprots Q7KZ19 P22680 P78454 Q3MIL8
Accessions AAA58423 AAA61350 EAW86811 P22680 BC101777 AAI01778 BC112184 AAI12185 M93133 AAA58435 X56088 CAA39568 XM_011517476 XP_011515778 NM_000780 NP_000771
Function Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. {ECO:0000269|PubMed:19965590}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Detected in liver. {ECO:0000269|PubMed:15796896}.
Top Pathways Primary bile acid biosynthesis, Steroid hormone biosynthesis, PPAR signaling pathway, Bile secretion

CYP7A1 CRISPR/Cas9 KO Plasmid (h) - sc-401001 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 HDR Plasmid (h) - sc-401001-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 Double Nickase Plasmid (h) - sc-401001-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 Double Nickase Plasmid (h2) - sc-401001-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 CRISPR Activation Plasmid (h) - sc-401001-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 CRISPR Activation Plasmid (h2) - sc-401001-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 Lentiviral Activation Particles (h) - sc-401001-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 Lentiviral Activation Particles (h2) - sc-401001-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP7A1 siRNA (h) - sc-41490 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP7A1 shRNA Plasmid (h) - sc-41490-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP7A1 shRNA (h) Lentiviral Particles - sc-41490-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP7A1 RNAi - H00001581-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU035211 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1808 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12661 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12661

CYP7A1 siRNA (Human) - CRH1110 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP7A1 - MBS8239709 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYP7A1 (NM_000780.3) - SHH273785 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CYP7A1(NM_000780.3) - SHG218013 from Creative biogene

Category siRNA
Species Reactivities Human

CYP7A1 shRNA Plasmid (Human) - CHH1110 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP7A1 miRNA 3'UTR clone - MiUTR3H-00416 from Creative biogene

Species Reactivities Human
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