CYP2A6

Gene Symbol CYP2A6
Entrez Gene 1548
Alt Symbol CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily A, polypeptide 6
Other Description 1,4-cineole 2-exo-monooxygenase|coumarin 7-hydroxylase|cytochrome P450 2A6|cytochrome P450 IIA3|cytochrome P450(I)|cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6|flavoprotein-linked monooxygenase|xenobiotic monooxygenase
Swissprots Q9H1Z7 Q16803 A7YAE5 Q4VAU0 Q4VAT9 Q9UK48 Q4VAU1 P10890 Q9UCU0 B2R7F6 P00190 P11509
Accessions AAB40518 AAG45229 ABV02584 ACK44068 EAW57012 P11509 AF182275 AAF13600 AK307740 AK309594 AK312964 BAG35803 BC096253 AAH96253 BC096254 AAH96254 BC096255 AAH96255 BC096256 AAH96256 DA641580 HQ258268 ADR83022 M33318 AAA52067 X06401 X13897 CAA32097 X13929 CAA32117 X13930 CAA32118 NM_000762 NP_000753
Function Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity. {ECO:0000269|PubMed:11695850, ECO:0000269|PubMed:16086027, ECO:0000269|PubMed:17125252, ECO:0000269|PubMed:18779312, ECO:0000269|PubMed:1889415, ECO:0000269|PubMed:1944238}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Liver. {ECO:0000269|PubMed:1889415, ECO:0000269|PubMed:1944238}.
Top Pathways Chemical carcinogenesis, Caffeine metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

CYP2A (H-110) - sc-33214 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2A (H-110): sc-33214. Western blot analysis of CYP2A expression in human liver (A) and mouse liver (B) tissue extracts.

CYP2A (K-20) - sc-9895 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2A (K-20): sc-9895. Western blot analysis of CYP2A expression in non-transfected: sc-117752 (A) and human CYP2A transfected: sc-128391 (B) 293T whole cell lysates.

CYP2A (C-20) - sc-9896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2A (C-20): sc-9896. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

CYP2A6 (F16 P2 D8) - sc-53615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2A6 (F16 P2 D8): sc-53615. Immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human liver tissue showing cytoplasmic staining.

Anti-Cytochrome P450 2A6 antibody - ab3570 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cytochrome P450 2A6 antibody - ab64890 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 2A6 antibody (ab64890) at 1/500 dilutionLane 1 : extracts from Jurkat cellsLane 2 : extracts from Jurkat cells with immunizing peptide at 10 µgLysates/proteins at 10 µg per lane.

Anti-Cytochrome P450 2A6 antibody - ab129885 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 2A6 antibody (ab129885) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : HeLa cell extractLane 3 : HeLa cell extract with synthesized peptide

Anti-Cytochrome P450 2A6 antibody - ab89633 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Cytochrome P450 2A6 antibody (ab89633) at 1 µg/ml + Human liver lysate at 50 µg

Anti-Cytochrome P450 2A6 antibody - ab133874 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 2A6 antibody (ab133874) at 1 µg/ml + Human fetal small intestine lysate at 10 µg

Anti-Cytochrome P450 2A6 antibody - ab125775 from Abcam

Host Sheep
Clonality Polyclonal

Anti-Cytochrome P450 2A6 antibody [1D2] - ab119783 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D2
All lanes : Anti-Cytochrome P450 2A6 antibody [1D2] (ab119783) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Cytochrome P450 2A6 cDNALysates/proteins at 5 µg per lane.

Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] - ab56069 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone F16 P2 D8
Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml

Anti-CYP2A6 Antibody (clone 2A8) - LS-C173463 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2A8
IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.

Anti-CYP2A6 Antibody (clone 5F8) - LS-C337537 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 5F8
IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CYP2A6 Antibody (clone 3C1) - LS-C173466 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 3C1
IHC of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody.

Anti-CYP2A6 Antibody (clone 9G3) - LS-C337610 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 9G3
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CYP2A6 Antibody (clone 1D2) - LS-C173480 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1D2
IHC of paraffin-embedded Human bladder tissue using anti-CYP2A6 mouse monoclonal antibody.

Anti-CYP2A6 Antibody - LS-C6337 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2A6 Antibody - LS-C6339 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2A6 Antibody - LS-C6340 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2A6 Antibody - LS-C64153 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2A6 Antibody - LS-C86038 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2A6 Antibody (aa1-494) - LS-C128488 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CYP2A6 Antibody - LS-C27024 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Left: Western blot of CYP2A6 antibody (LS-C27024) on recombinant cytochrome p450 at 1 ug/ml. Right: Staining using CYP2A6 antibody on normal human liver tissue at 1 ug/ml.

Anti-CYP2A6 Antibody (aa352-401) - LS-C151387 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2A6 antibody Western Blot of Fetal Small Intestine.
Search more