CYP2A6

Gene Symbol CYP2A6
Entrez Gene 1548
Alt Symbol CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily A, polypeptide 6
Other Description 1,4-cineole 2-exo-monooxygenase|coumarin 7-hydroxylase|cytochrome P450 2A6|cytochrome P450 IIA3|cytochrome P450(I)|cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6|flavoprotein-linked monooxygenase|xenobiotic monooxygenase
Swissprots Q9H1Z7 Q16803 A7YAE5 Q4VAU0 Q4VAT9 Q9UK48 Q4VAU1 P10890 Q9UCU0 B2R7F6 P00190 P11509
Accessions AAB40518 AAG45229 ABV02584 ACK44068 EAW57012 P11509 AF182275 AAF13600 AK307740 AK309594 AK312964 BAG35803 BC096253 AAH96253 BC096254 AAH96254 BC096255 AAH96255 BC096256 AAH96256 DA641580 HQ258268 ADR83022 M33318 AAA52067 X06401 X13897 CAA32097 X13929 CAA32117 X13930 CAA32118 NM_000762 NP_000753
Function Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity. {ECO:0000269|PubMed:11695850, ECO:0000269|PubMed:16086027, ECO:0000269|PubMed:17125252, ECO:0000269|PubMed:18779312, ECO:0000269|PubMed:1889415, ECO:0000269|PubMed:1944238}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Liver. {ECO:0000269|PubMed:1889415, ECO:0000269|PubMed:1944238}.
Top Pathways Chemical carcinogenesis, Caffeine metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

CYP2A6 CRISPR/Cas9 KO Plasmid (h) - sc-403448 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 HDR Plasmid (h) - sc-403448-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 Double Nickase Plasmid (h) - sc-403448-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 Double Nickase Plasmid (h2) - sc-403448-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 CRISPR Activation Plasmid (h) - sc-403448-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 CRISPR Activation Plasmid (h2) - sc-403448-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 Lentiviral Activation Particles (h) - sc-403448-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 Lentiviral Activation Particles (h2) - sc-403448-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 siRNA (h) - sc-105253 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP2A6 shRNA Plasmid (h) - sc-105253-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP2A6 shRNA (h) Lentiviral Particles - sc-105253-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytochrome P450 2A6 RNAi - H00001548-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6881 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6881 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01687 from Sigma-Aldrich

Category miRNA

CYP2A6 siRNA (Human) - CRH1093 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP2A6 - MBS8235828 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP2A6 CRISPR/Cas9 KO Plasmid (h2) - sc-403448-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP2A6 HDR Plasmid (h2) - sc-403448-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human CYP2A6 siRNA - orb261595 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP2A6 shRNA Plasmid (Human) - CHH1093 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP2A6 miRNA 3'UTR clone - MiUTR3H-00540 from Creative biogene

Species Reactivities Human
Search more