| Gene Symbol |
PLA2G2E
|
| Entrez Gene |
30814
|
| Alt Symbol |
GIIE sPLA2, sPLA2-IIE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IIE
|
| Other Description |
group IIE secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2E
|
| Swissprots |
Q5VXJ8 Q9NZK7
|
| Accessions |
EAW94906 Q9NZK7 AF189279 AAF36541 BC069116 AAH69116 BC140240 AAI40241 BC141619 AAI41620 NM_014589 NP_055404
|
| Function |
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Restricted to the brain, heart, lung, and placenta.
|
| Top Pathways |
Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism
|