Gene Symbol | PLA2G2E |
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Entrez Gene | 30814 |
Alt Symbol | GIIE sPLA2, sPLA2-IIE |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group IIE |
Other Description | group IIE secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2E |
Swissprots | Q5VXJ8 Q9NZK7 |
Accessions | EAW94906 Q9NZK7 AF189279 AAF36541 BC069116 AAH69116 BC140240 AAI40241 BC141619 AAI41620 NM_014589 NP_055404 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids. |
Subcellular Location | Secreted. |
Tissue Specificity | Restricted to the brain, heart, lung, and placenta. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group IIE sPLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-408058 from Santa Cruz Biotechnology
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group IIE sPLA 2 HDR Plasmid (h) - sc-408058-HDR from Santa Cruz Biotechnology
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group IIE sPLA 2 Double Nickase Plasmid (h) - sc-408058-NIC from Santa Cruz Biotechnology
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group IIE sPLA 2 Double Nickase Plasmid (h2) - sc-408058-NIC-2 from Santa Cruz Biotechnology
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group IIE sPLA 2 CRISPR Activation Plasmid (h) - sc-408058-ACT from Santa Cruz Biotechnology
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group IIE sPLA 2 CRISPR Activation Plasmid (h2) - sc-408058-ACT-2 from Santa Cruz Biotechnology
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group IIE sPLA 2 Lentiviral Activation Particles (h) - sc-408058-LAC from Santa Cruz Biotechnology
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group IIE sPLA 2 Lentiviral Activation Particles (h2) - sc-408058-LAC-2 from Santa Cruz Biotechnology
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group IIE sPLA 2 siRNA (h) - sc-88254 from Santa Cruz Biotechnology
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group IIE sPLA 2 shRNA Plasmid (h) - sc-88254-SH from Santa Cruz Biotechnology
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group IIE sPLA 2 shRNA (h) Lentiviral Particles - sc-88254-V from Santa Cruz Biotechnology
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Phospholipase A2 IIE RNAi - H00030814-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16891 from Sigma-Aldrich
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PLA2G2E siRNA (Human) - CRH9341 from Cohesion Biosciences
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shRNA set against Human Pla2g2e (NM_014589.1) - SHH376772 from Creative biogene
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shRNA set against Human PLA2G2E(NM_014589.1) - SHR118876 from Creative biogene
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PLA2G2E shRNA Plasmid (Human) - CHH9341 from Cohesion Biosciences
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PLA2G2E miRNA 3'UTR clone - MiUTR1H-07957 from Creative biogene
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