| Gene Symbol |
PLA2G2E
|
| Entrez Gene |
30814
|
| Alt Symbol |
GIIE sPLA2, sPLA2-IIE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IIE
|
| Other Description |
group IIE secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2E
|
| Swissprots |
Q5VXJ8 Q9NZK7
|
| Accessions |
EAW94906 Q9NZK7 AF189279 AAF36541 BC069116 AAH69116 BC140240 AAI40241 BC141619 AAI41620 NM_014589 NP_055404
|
| Function |
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Restricted to the brain, heart, lung, and placenta.
|
| Top Pathways |
Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism
|
![Western Blot: Phospholipase A2 IIE Overexpression Lysate (Adult Normal) [NBP2-10315] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phospholipase A2 IIE.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4561_Phospholipase%2520A2%2520IIE%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10315-img0001.jpg)