UGT1A8

Gene Symbol UGT1A8
Entrez Gene 54576
Alt Symbol UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A8
Other Description UDP glycosyltransferase 1 family, polypeptide A8|UDP-glucuronosyltransferase 1 family polypeptide A8s|UDP-glucuronosyltransferase 1-8|UDP-glucuronosyltransferase 1-H|UDP-glucuronosyltransferase 1A8
Swissprots Q8WX85 Q8TEX4 Q9HAW9 Q8WTQ9 B8K290 B2R8S3 O14928
Accessions AAA86625 AAG30416 AAL73506 AAL73507 AAL73508 AAX47026 AAX47027 AAX47028 AAX47029 AAX47030 AAX47031 AAX47032 AAY24023 EAW71057 Q9HAW9 AF030310 AAB84259 AF462267 AAL75963 AF462268 AAL75964 AK313488 BAG36270 AY435143 AAR95644 BC156848 AAI56849 DQ364251 ABC96775 NM_019076 NP_061949
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:19545173}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Colon specific. Isoform 1 and 2 are expressed in liver, kidney, colon and small intestine; isoform 2 but not isoform 1 is expressed in liver (PubMed:18004212). {ECO:0000269|PubMed:18004212, ECO:0000269|PubMed:9535849}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

UDP glucuronosyltransferase 1 family, polypeptide A8 (UGT1A8) - TP314521 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
UDP glucuronosyltransferase 1 family, polypeptide A8 (UGT1A8)

UGT1A8 Peptide, Human - M34GP17052H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human UGT1A8 Protein, MYC/DDK-tagged - UGT1A8-511H from Creative Biomart

Category Protein
Source HEK293
Species Human
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