UGT1A8

Gene Symbol UGT1A8
Entrez Gene 54576
Alt Symbol UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H
Species Human
Gene Type protein-coding
Description UDP glucuronosyltransferase 1 family, polypeptide A8
Other Description UDP glycosyltransferase 1 family, polypeptide A8|UDP-glucuronosyltransferase 1 family polypeptide A8s|UDP-glucuronosyltransferase 1-8|UDP-glucuronosyltransferase 1-H|UDP-glucuronosyltransferase 1A8
Swissprots Q8WX85 Q8TEX4 Q9HAW9 Q8WTQ9 B8K290 B2R8S3 O14928
Accessions AAA86625 AAG30416 AAL73506 AAL73507 AAL73508 AAX47026 AAX47027 AAX47028 AAX47029 AAX47030 AAX47031 AAX47032 AAY24023 EAW71057 Q9HAW9 AF030310 AAB84259 AF462267 AAL75963 AF462268 AAL75964 AK313488 BAG36270 AY435143 AAR95644 BC156848 AAI56849 DQ364251 ABC96775 NM_019076 NP_061949
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:19545173}.
Subcellular Location Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Colon specific. Isoform 1 and 2 are expressed in liver, kidney, colon and small intestine; isoform 2 but not isoform 1 is expressed in liver (PubMed:18004212). {ECO:0000269|PubMed:18004212, ECO:0000269|PubMed:9535849}.
Top Pathways Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450

UGT1A CRISPR/Cas9 KO Plasmid (h) - sc-417594 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A HDR Plasmid (h) - sc-417594-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A Double Nickase Plasmid (h) - sc-417594-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A Double Nickase Plasmid (h2) - sc-417594-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A CRISPR Activation Plasmid (h) - sc-417594-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A CRISPR Activation Plasmid (h2) - sc-417594-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A Lentiviral Activation Particles (h) - sc-417594-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A Lentiviral Activation Particles (h2) - sc-417594-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UGT1A siRNA (h2) - sc-44476 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UGT1A shRNA Plasmid (h2) - sc-44476-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UGT1A shRNA (h2) Lentiviral Particles - sc-44476-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN22463 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22463 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06217 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06217

UGT1A8 siRNA (Human) - CRJ0141 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UGT1A8 - MBS8232195 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UGT1A8 (NM_019076.4) - SHH440120 from Creative biogene

Category siRNA
Species Reactivities Human

Human UGT1A8 siRNA - orb270642 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UGT1A8 shRNA Plasmid (Human) - CHJ0141 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UGT1A8 miRNA 3'UTR clone - MiUTR1H-10994 from Creative biogene

Species Reactivities Human
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