ZDHHC17

Gene Symbol ZDHHC17
Entrez Gene 23390
Alt Symbol HIP14, HIP3, HSPC294, HYPH
Species Human
Gene Type protein-coding
Description zinc finger, DHHC-type containing 17
Other Description DHHC-17|HIP-14|HIP-3|Huntingtin interacting protein H|huntingtin interacting protein 14|huntingtin interacting protein 3|huntingtin yeast partner H|huntingtin-interacting protein 14|huntingtin-interacting protein 3|huntingtin-interacting protein H|palmitoyltransferase ZDHHC17|putative MAPK-activating protein PM11|putative NF-kappa-B-activating protein 205|zinc finger DHHC domain-containing protein 17|zinc finger, DHHC domain containing 17
Swissprots B4DR39 Q9P088 O75407 Q8IUH5 Q7Z2I0 Q9UPZ8 Q86W89 Q86YK0
Accessions EAW97331 EAW97332 EAW97333 EAW97334 EAW97335 Q8IUH5 AB023163 BAA76790 AB024494 BAC22089 AB097013 BAC77366 AB097035 BAC77388 AF049612 AAC26848 AF161412 AAF28972 AK292866 BAF85555 AK299089 BAG61151 BC030990 AAH30990 BC050324 AAH50324 DA227374 XM_005268749 XP_005268806 XM_005268750 XP_005268807 XM_005268751 XP_005268808 XM_011538083 XP_011536385 XM_011538084 XP_011536386 XR_944512 NM_015336 NP_056151
Function Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. Palmitoylates MPP1 in erythrocytes. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg(2+) transport. {ECO:0000269|PubMed:12393793, ECO:0000269|PubMed:15489887, ECO:0000269|PubMed:15603740, ECO:0000269|PubMed:18794299, ECO:0000269|PubMed:19139280, ECO:0000269|PubMed:22496366}.
Subcellular Location Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi membrane vesicles.
Tissue Specificity Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. ZDHHC17 is the only palmitoyltransferase in erythrocytes. {ECO:0000269|PubMed:12393793, ECO:0000269|PubMed:22496366}.

HIP3 (K-14) - sc-69424 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HIP3 (T-20) - sc-69425 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ZDHHC17 antibody - ab31298 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-ZDHHC17 antibody (ab31298) at 1 µg/ml + Mouse Brain lysate (35µg protein in RIPA buffer)Observed band size : 70 kDa (why is the actual band size different from the predicted?)

Anti-ZDHHC17 antibody - N-terminal - ab187323 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-ZDHHC17 antibody - N-terminal (ab187323) at 1/1000 dilution + Mouse brain total cell extract

Anti-ZDHHC17 Antibody (aa311-360) - LS-C82812 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-ZDHHC17 Antibody (aa398-447) - LS-C82500 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ZDHHC17 Antibody (aa621-632) IHC-plus™ - LS-B9497 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ZDHHC17 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ZDHHC17 Antibody - NBP1-59039 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

ZDHHC17 Antibody - NBP1-81748 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZDHHC17 Antibody [NBP1-81748] - Staining of human cell line A-431 shows positivity in golgi apparatus & vesicles.

ZDHHC17 Antibody - NBP2-20941 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZDHHC17 Antibody [NBP2-20941] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:3000.

ZDHHC17 Antibody - NB100-1505 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: ZDHHC17 Antibody [NB100-1505] - (1ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ZDHHC17 Polyclonal Antibody - bs-6628R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HIP14 antibody produced in rabbit - H7414 from Sigma-Aldrich

Prices $69.10, $392.50
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Whole cell lysates and brain extracts (P2 membrane fractions) were separated on SDS-PAGE and blotted with Anti-HIP14 (<B>Cat. No. H7414</B>). The antibody was developed with Goat Anti-Rabbit IgG, Peroxidase conjugate (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. Antibody dilution 1:4,000<BR/><B>Lanes</B><BR/>1: HEK-293T cells transfected with human HIP14-FLAG<BR/>2: Untransfected HEK-293T cells<BR/>3: HEK-293T cells transfected with human HIP14-FLAG + Inhibition with HIP14 (immunizing peptide human 614-632) (20 μg/mL)<BR/>4: Mouse brain (membrane P2 fraction)<BR/>5: Rat brain (membrane P2 fraction)

Anti-ZDHHC17 (AB2) antibody produced in rabbit - AV47142 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: Jurkat (<B>Cat. No. AV47142</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 5.0 μg/mL in cell type Jurkat

Anti-ZDHHC17 antibody produced in rabbit - HPA016807 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZDHHC17: <B>Cat. No. HPA016807</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

Anti-HIP14/ZDHHC17 antibody produced in goat - SAB2500508 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HIP14 / ZDHHC17: <B>Cat. No. SAB2500508</B>: (1 μg/mL) staining of Mouse Brain lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ZDHHC17 antibody - middle region (ARP47141_P050) - ARP47141_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZDHHC17 antibody - middle region (ARP47142_T100) - ARP47142_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HIP14--ZDHHC17-Antibody - AF1525a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1525a (1 µg/ml) staining of Mouse Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HIP14 / ZDHHC17 antibody, C-term - GTX89582 from GeneTex

Prices $299.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-HIP14 / ZDHHC17 antibody, C-term used in Western blot. GTX89582

Goat Anti-HIP14 / ZDHHC17 Antibody (OAEB02259) - OAEB02259 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ZDHHC17 antibody - 70R-1832 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ZDHHC17 antibody - 70R-5970 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

ZDHHC17 Polyclonal Antibody - A4545 from ABclonal

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

ZDHHC17 antibody (FITC) - orb103745 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
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