Gene Symbol | CASS4 |
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Entrez Gene | 57091 |
Alt Symbol | C20orf32, CAS4, HEFL, HEPL |
Species | Human |
Gene Type | protein-coding |
Description | Cas scaffolding protein family member 4 |
Other Description | HEF-like protein|HEF1-EFS-p130Cas-like protein|cas scaffolding protein family member 4 |
Swissprots | Q9NQ75 Q9BYL5 Q96K09 E1P5Z8 Q5QPD6 |
Accessions | EAW75541 EAW75542 EAW75543 EAW75544 EAW75545 EAW75546 EAW75547 Q9NQ75 AJ276678 CAC00655 AK027760 BAB55351 AK295613 BAG58496 AK308057 AK314653 BC027951 AAH27951 BX280195 DA584687 XM_006723831 XP_006723894 NM_001164114 NP_001157586 NM_001164115 NP_001157587 NM_001164116 NP_001157588 NM_020356 NP_065089 |
Function | Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. {ECO:0000269|PubMed:18256281}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18256281}. Cell junction, focal adhesion {ECO:0000269|PubMed:18256281}. |
Tissue Specificity | Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines. {ECO:0000269|PubMed:18256281}. |
CAS4 (H-3) - sc-376968 from Santa Cruz Biotechnology
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CAS4 (N-20) - sc-85412 from Santa Cruz Biotechnology
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CAS4 (P-14) - sc-85413 from Santa Cruz Biotechnology
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CAS4 (E-19) - sc-85411 from Santa Cruz Biotechnology
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Anti-CASS4 antibody - ab116022 from Abcam
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Anti-CASS4 antibody [EPR8947(2)] - ab157198 from Abcam
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Anti-CASS4 Antibody (aa609-639, AP) - LS-C233380 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639, APC) - LS-C233381 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639, FITC) - LS-C233384 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639) - LS-C329312 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639, Azide-free, HRP) - LS-C249572 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639, Biotin) - LS-C233383 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa609-639, PE) - LS-C233387 from LifeSpan Bioscience
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Anti-CASS4 Antibody (N-Terminus) - LS-C201697 from LifeSpan Bioscience
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Anti-CASS4 Antibody (aa610-639) - LS-C168336 from LifeSpan Bioscience
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CASS4 Antibody - H00057091-B01 from Novus Biologicals
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ANTI-CASS4 (C-TERM) antibody produced in rabbit - SAB1304501 from Sigma-Aldrich
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Anti-CASS4 antibody produced in rabbit - HPA012659 from Sigma-Aldrich
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CASS4 Antibody - N-terminal region (ARP57390_P050) - ARP57390_P050 from Aviva Systems Biology
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CASS4-Antibody-C-term - AP13515b from Abgent, a WuXi AppTec company
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CASS4 Antibody - C-terminal region (OAAB09809) - OAAB09809 from Aviva Systems Biology
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Anti -CASS4, CT (CASS4, C20orf32, HEFL, Cas scaffolding protein family member 4, HEF-likeprotein, HEF1-EFS-p130Cas-like protein) - 033222 from USBiological Life Science
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Anti -CASS4, CT (CASS4, C20orf32, HEFL, Cas scaffolding protein family member 4, HEF-likeprotein, HEF1-EFS-p130Cas-like protein) (AP) - 033222-AP from USBiological Life Science
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Anti -CASS4, CT (CASS4, C20orf32, HEFL, Cas scaffolding protein family member 4, HEF-likeprotein, HEF1-EFS-p130Cas-like protein) (APC) - 033222-APC from USBiological Life Science
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Anti -CASS4, CT (CASS4, C20orf32, HEFL, Cas scaffolding protein family member 4, HEF-likeprotein, HEF1-EFS-p130Cas-like protein) (Azide free) (HRP) - 033222-HRP from USBiological Life Science
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