Gene Symbol | CASS4 |
---|---|
Entrez Gene | 57091 |
Alt Symbol | C20orf32, CAS4, HEFL, HEPL |
Species | Human |
Gene Type | protein-coding |
Description | Cas scaffolding protein family member 4 |
Other Description | HEF-like protein|HEF1-EFS-p130Cas-like protein|cas scaffolding protein family member 4 |
Swissprots | Q9NQ75 Q9BYL5 Q96K09 E1P5Z8 Q5QPD6 |
Accessions | EAW75541 EAW75542 EAW75543 EAW75544 EAW75545 EAW75546 EAW75547 Q9NQ75 AJ276678 CAC00655 AK027760 BAB55351 AK295613 BAG58496 AK308057 AK314653 BC027951 AAH27951 BX280195 DA584687 XM_006723831 XP_006723894 NM_001164114 NP_001157586 NM_001164115 NP_001157587 NM_001164116 NP_001157588 NM_020356 NP_065089 |
Function | Docking protein that plays a role in tyrosine kinase- based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading. {ECO:0000269|PubMed:18256281}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18256281}. Cell junction, focal adhesion {ECO:0000269|PubMed:18256281}. |
Tissue Specificity | Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines. {ECO:0000269|PubMed:18256281}. |
CAS4 CRISPR/Cas9 KO Plasmid (h) - sc-406534 from Santa Cruz Biotechnology
|
||||||||
CAS4 HDR Plasmid (h) - sc-406534-HDR from Santa Cruz Biotechnology
|
||||||||
CAS4 Double Nickase Plasmid (h) - sc-406534-NIC from Santa Cruz Biotechnology
|
||||||||
CAS4 Double Nickase Plasmid (h2) - sc-406534-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CAS4 CRISPR Activation Plasmid (h) - sc-406534-ACT from Santa Cruz Biotechnology
|
||||||||
CAS4 CRISPR Activation Plasmid (h2) - sc-406534-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CAS4 Lentiviral Activation Particles (h) - sc-406534-LAC from Santa Cruz Biotechnology
|
||||||||
CAS4 Lentiviral Activation Particles (h2) - sc-406534-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CAS4 siRNA (h) - sc-72733 from Santa Cruz Biotechnology
|
||||||||
CAS4 shRNA Plasmid (h) - sc-72733-SH from Santa Cruz Biotechnology
|
||||||||
CAS4 shRNA (h) Lentiviral Particles - sc-72733-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU135331 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5392 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5392 from Sigma-Aldrich
|
||||||||
CASS4 siRNA (Human) - CRJ1313 from Cohesion Biosciences
|
||||||||
CASS4 RNAi - H00057091-R02 from Novus Biologicals
|
||||||||
CASS4 - MBS8241148 from MyBioSource
|
||||||||
shRNA set against Human CASS4 (NM_020356.3) - SHH255097 from Creative biogene
|
||||||||
CASS4 shRNA Plasmid (Human) - CHJ1313 from Cohesion Biosciences
|
||||||||
CASS4 miRNA 3'UTR clone - MiUTR3H-14290 from Creative biogene
|
||||||||
CASS4 miRNA 3'UTR clone - MiUTR3H-14291 from Creative biogene
|
||||||||
CASS4 miRNA 3'UTR clone - MiUTR3H-14292 from Creative biogene
|