WIPF1

Gene Symbol	WIPF1
Entrez Gene	7456
Alt Symbol	PRPL-2, WAS2, WASPIP, WIP
Species	Human
Gene Type	protein-coding
Description	WAS/WASL interacting protein family, member 1
Other Description	WAS/WASL-interacting protein family member 1|WASP-interacting protein|Wiskott-Aldrich syndrome protein interacting protein|protein PRPL-2
Swissprots	Q6MZU9 B8ZZM1 O43516 Q53TA9 Q9BU37 D3DPE4 Q9UNP1 Q15220
Accessions	AAY14708 EAX11129 EAX11130 EAX11131 EAX11132 EAX11133 EAX11134 EAX11135 O43516 AA599214 AA903457 AF031588 AAC03767 AF106062 AAD45972 AK097901 AK301271 BAG62833 AK304194 BAG65074 AL529597 AL832275 BC002914 AAH02914 BC045584 BC110288 AAI10289 BG820214 BM475558 BM542331 BQ016063 BQ441937 BX640870 CAE45928 DA674627 EU832147 ACE87497 EU832240 ACE86810 X86019 CAA60014 XM_011511780 XP_011510082 XM_011511781 XP_011510083 NM_001077269 NP_001070737 NM_003387 NP_003378
Function	Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus. {ECO:0000250, ECO:0000269|PubMed:10878810, ECO:0000269|PubMed:19910490, ECO:0000269|PubMed:9405671}.
Subcellular Location	Cytoplasmic vesicle {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, ruffle {ECO:0000269|PubMed:19910490}. Note=Vesicle surfaces and along actin tails. Colocalizes with actin stress fibers. When coexpressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL (By similarity). {ECO:0000250}.
Tissue Specificity	Highly expressed in peripheral blood mononuclear cells, spleen, placenta, small intestine, colon and thymus. Lower expression in ovary, heart, brain, lung, liver, skeletal muscle, kidney, pancreas, prostate and testis. {ECO:0000269|PubMed:9405671}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WIPF1 full length protein - ab132512 from Abcam Category Protein Source Wheat germ Species Human

WIPF1 peptide - ab107711 from Abcam Category Peptide

WIPF1 / WIP Antibody Blocking Peptide - LS-E21480 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WIPF1 / WIP Antibody Blocking Peptide - LS-E26390 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human WIPF1/WIP Protein - H00007456-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

WIPF1 blocking peptide - GTX89003-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

WIPF1 Peptide - AC21-1226-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

WIPF1 - H00007456-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

WIPF1 - H00007456-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

WIPF1 Peptide - 46-596P from ProSci Category Peptide Species Human

WIPF1 fusion protein - Ag16975 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

WIPF1 fusion protein - ag14168 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

WIP (Y455) Peptide - BS9169P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human WAS/WASL-interacting protein family member 1(WIPF1) - CSB-YP026114HU CSB-EP026114HU CSB-BP026114HU CSB-MP026114HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WIPF1 (transcript variant 2) - TP312019 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

WIPF1 (transcript variant 1) - TP317601 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

WAS/WASL-interacting protein family member 1 (WIPF1) , Recombinant Protein - MBS1089287 from MyBioSource Category Protein Prices $2,120.00, $2,120.00, $2,585.00, $2,585.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

WIPF1, Peptide - MBS425822 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

WIPF1, Peptide - MBS658113 from MyBioSource Category Peptide Prices $340.00 Sizes 100 µg Species Human, Rat, Dog

WIPF1 Blocking Peptide - abx061118 from Abbexa Category Peptide Species Human, Mouse, Rat

WIPF1/WIP Recombinant Protein Antigen - NBP1-86859PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WIPF1 Peptide, Human - M34GP17497H from Creative Peptides Category Peptide Source Synthetic. Species Human

WIPF1 Blocking Peptide - CBP5031 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

WIPF1 Immunizing peptide - orb17470 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

WIPF1/WIP Recombinant Protein Antigen - NBP2-57654PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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