| Gene Symbol |
SNTG2
|
| Entrez Gene |
54221
|
| Alt Symbol |
G2SYN, SYN5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syntrophin, gamma 2
|
| Other Description |
gamma-2-syntrophin|syntrophin-5
|
| Swissprots |
Q05AH5 Q9NY99
|
| Accessions |
EAX01092 Q9NY99 AJ003029 CAB92969 BC035783 BC125251 AAI25252 BG208326 XM_011510364 XP_011508666 XM_011510365 XP_011508667 XM_011510366 XP_011508668 XM_011510367 XP_011508669 XM_011510368 XP_011508670 NM_018968 NP_061841
|
| Function |
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
|
| Tissue Specificity |
Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. {ECO:0000269|PubMed:10747910}.
|
![Western Blot: Syntrophin gamma 2 Overexpression Lysate (Adult Normal) [NBP2-06752] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Syntrophin gamma 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4816_Syntrophin%2520gamma%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06752-img0001.jpg)