| Gene Symbol | SNTG2 |
|---|---|
| Entrez Gene | 54221 |
| Alt Symbol | G2SYN, SYN5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | syntrophin, gamma 2 |
| Other Description | gamma-2-syntrophin|syntrophin-5 |
| Swissprots | Q05AH5 Q9NY99 |
| Accessions | EAX01092 Q9NY99 AJ003029 CAB92969 BC035783 BC125251 AAI25252 BG208326 XM_011510364 XP_011508666 XM_011510365 XP_011508667 XM_011510366 XP_011508668 XM_011510367 XP_011508669 XM_011510368 XP_011508670 NM_018968 NP_061841 |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane. |
| Tissue Specificity | Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. {ECO:0000269|PubMed:10747910}. |